Torres J, Mehandru S, Colombel JF, Peyrin-Biroulet L. Crohn’s disease. Lancet. 2017;389:1741–55.
Article
PubMed
Google Scholar
Ungaro R, Mehandru S, Allen PB, Peyrin-Biroulet L, Colombel JF. Ulcerative colitis. Lancet. 2017;389:1756–70.
Article
PubMed
Google Scholar
Gecse KB, Vermeire S. Differential diagnosis of inflammatory bowel disease: imitations and complications. Lancet Gastroenterol Hepatol. 2018;3:644–53.
Article
PubMed
Google Scholar
Burisch J, Munkholm P. The epidemiology of inflammatory bowel disease. Scand J Gastroenterol. 2015;50:942–51.
Article
PubMed
Google Scholar
Ng SC, Shi HY, Hamidi N, Underwood FE, Tang W, Benchimol EI, Panaccione R, Ghosh S, Wu JCY, Chan FKL, Sung JJY, Kaplan GG. Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies. Lancet. 2017;390:2769–78.
Article
PubMed
Google Scholar
Loftus EV Jr. Update on the incidence and prevalence of inflammatory bowel disease in the United States. Gastroenterol Hepatol. 2016;12:704–7.
Google Scholar
Wilson J, Hair C, Knight R, Catto-Smith A, Bell S, Kamm M, Desmond P, McNeil J, Connell W. High incidence of inflammatory bowel disease in Australia: a prospective population-based Australian incidence study. Inflamm Bowel Dis. 2010;16:1550–6.
Article
PubMed
Google Scholar
Hanauer SB. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm Bowel Dis. 2006;12(Suppl 1):S3–9.
Article
PubMed
Google Scholar
King JA, Underwood FE, Panaccione N, Quan J, Windsor JW, Kotze PG, Ng SC, Ghosh S, Lakatos PL, Jess T, Panaccione R, Seow CH, Ben-Horin S, Burisch J, Colombel JF, Loftus EV Jr, Gearry R, Halfvarson J, Kaplan GG. Trends in hospitalisation rates for inflammatory bowel disease in western versus newly industrialised countries: a population-based study of countries in the Organisation for Economic Co-operation and Development. Lancet Gastroenterol Hepatol. 2019;4:287–95.
Article
PubMed
Google Scholar
El Mouzan MI, Saadah O, Al-Saleem K, Al Edreesi M, Hasosah M, Alanazi A, Al Mofarreh M, Asery A, Al Qourain A, Nouli K, Al Hussaini A, Telmesani A, AlReheili K, Alghamdi S, Alrobiaa N, Alzaben A, Mehmadi A, Al Hebbi H, Al Sarkhy A, Al Mehaidib A, Al Saleem B, Assiri A, Wali S. Incidence of pediatric inflammatory bowel disease in Saudi Arabia: a multicenter national study. Inflamm Bowel Dis. 2014;20:1085–90.
PubMed
Google Scholar
Al-Ghamdi AS, Al-Mofleh IA, Al-Rashed RS, Al-Amri SM, Aljebreen AM, Isnani AC, El-Badawi R. Epidemiology and outcome of Crohn’s disease in a teaching hospital in Riyadh. World J Gastroenterol. 2004;10:1341–4.
Article
PubMed
PubMed Central
Google Scholar
Al-Mofarreh MA, Al-Mofleh IA. Emerging inflammatory bowel disease in Saudi outpatients: a report of 693 cases. Saudi J Gastroenterol. 2013;19:16–22.
Article
PubMed
PubMed Central
Google Scholar
Fadda MA, Peedikayil MC, Kagevi I, Kahtani KA, Ben AA, Al HI, Sohaibani FA, Quaiz MA, Abdulla M, Khan MQ, Helmy A. Inflammatory bowel disease in Saudi Arabia: a hospital-based clinical study of 312 patients. Ann Saudi Med. 2012;32:276–82.
Article
PubMed
PubMed Central
Google Scholar
Alharbi OR, Azzam NA, Almalki AS, Almadi MA, Alswat KA, Sadaf N, Aljebreen AM. Clinical epidemiology of ulcerative colitis in Arabs based on the Montréal classification. World J Gastroenterol. 2014;20:17525–31.
Article
PubMed
PubMed Central
Google Scholar
Aljebreen AM, Alharbi OR, Azzam NA, Almalki AS, Alswat KA, Almadi MA. Clinical epidemiology and phenotypic characteristics of Crohn’s disease in the central region of Saudi Arabia. Saudi J Gastroenterol. 2014;20:162–9.
Article
PubMed
PubMed Central
Google Scholar
Kozuch PL, Hanauer SB. Treatment of inflammatory bowel disease: a review of medical therapy. World J Gastroenterol. 2008;14:354–77.
Article
CAS
PubMed
PubMed Central
Google Scholar
Feuerstein JD, Cheifetz AS. Crohn disease: epidemiology, diagnosis, and management. Mayo Clin Proc. 2017;92:1088–103.
Article
CAS
PubMed
Google Scholar
Hemperly A, Vande Casteele N, Sandborn WJ. Clinical pharmacology in adult and pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2018;24:2527–42.
Article
PubMed
Google Scholar
Rawla P, Sunkara T, Raj JP. Role of biologics and biosimilars in inflammatory bowel disease: current trends and future perspectives. J Inflamm Res. 2018;11:215–26.
Article
CAS
PubMed
PubMed Central
Google Scholar
Schnitzler F, Fidder H, Ferrante M, Noman M, Arijs I, Van Assche G, Hoffman I, Van Steen K, Vermeire S, Rutgeerts P. Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn’s disease. Inflamm Bowel Dis. 2009;15:1295–301.
Article
PubMed
Google Scholar
Casellas F, Barreiro de Acosta M, Iglesias M, Robles V, Nos P, Aguas M, Riestra S, de Francisco R, Papo M, Borruel N. Mucosal healing restores normal health and quality of life in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2012;24:762–9.
Article
PubMed
Google Scholar
Holko P, Kawalec P, Mossakowska M. Quality of life related to oral, subcutaneous, and intravenous biologic treatment of inflammatory bowel disease: a time trade-off study. Eur J Gastroenterol Hepatol. 2018;30:174–80.
Article
PubMed
Google Scholar
Rencz F, Péntek M, Bortlik M, Zagorowicz E, Hlavaty T, Śliwczyński A, Diculescu MM, Kupcinskas L, Gecse KB, Gulácsi L, Lakatos PL. Biological therapy in inflammatory bowel diseases: access in Central and Eastern Europe. World J Gastroenterol. 2015;21:1728–37.
Article
PubMed
PubMed Central
Google Scholar
Yu H, MacIsaac D, Wong JJ, Sellers ZM, Wren AA, Bensen R, Kin C, Park KT. Market share and costs of biologic therapies for inflammatory bowel disease in the USA. Aliment Pharmacol Ther. 2018;47:364–70.
Article
CAS
PubMed
Google Scholar
Yu AP, Cabanilla LA, Wu EQ, Mulani PM, Chao J. The costs of Crohn’s disease in the United States and other Western countries: a systematic review. Curr Med Res Opin. 2008;24:319–28.
Article
CAS
PubMed
Google Scholar
Cohen RD, Yu AP, Wu EQ, Xie J, Mulani PM, Chao J. Systematic review: the costs of ulcerative colitis in Western countries. Aliment Pharmacol Ther. 2010;31:693–707.
Article
CAS
PubMed
Google Scholar
Kaplan GG. The global burden of IBD: from 2015 to 2025. Nat Rev Gastroenterol Hepatol. 2015;12:720–7.
Article
PubMed
Google Scholar
van der Valk ME, Mangen MJ, Leenders M, Dijkstra G, van Bodegraven AA, Fidder HH, de Jong DJ, Pierik M, van der Woude CJ, Romberg-Camps MJ, Clemens CH, Jansen JM, Mahmmod N, van de Meeberg PC, van der Meulen-de Jong AE, Ponsioen CY, Bolwerk CJ, Vermeijden JR, Siersema PD, van Oijen MG, Oldenburg B. Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNF-α therapy: results from the COIN study. Gut. 2014;63:72–9.
Article
PubMed
Google Scholar
Park KT, Colletti RB, Rubin DT, Sharma BK, Thompson A, Krueger A. Health insurance paid costs and drivers of costs for patients with Crohn’s disease in the United States. Am J Gastroenterol. 2016;111:15–23.
Article
CAS
PubMed
Google Scholar
Sketris IS, Metge CJ, Ross JL, MacCara ME, Comeau DG, Kephart GC, Blackburn JL. The use of the World Health Organisation anatomical therapeutic chemical/defined daily dose methodology in Canada. Drug Inf J. 2004;38:15–27.
Article
Google Scholar
Mowat C, Cole A, Windsor A, Ahmad T, Arnott I, Driscoll R, Mitton S, Orchard T, Rutter M, Younge L, Lees C, Ho GT, Satsangi J, Bloom S. Guidelines for the management of inflammatory bowel disease in adults. Gut. 2011;60:571–607.
Article
PubMed
Google Scholar
Gulacsi L, Pentek M, Rencz F, Brodszky V, Baji P, Vegh Z, Gecse KB, Danese S, Peyrin-Biroulet L, Lakatos PL. Biosimilars for the management of inflammatory bowel diseases: economic considerations. Curr Med Chem. 2019;26:259–69.
Article
CAS
PubMed
Google Scholar
Stone CD. The economic burden of inflammatory bowel disease: clear problem, unclear solution. Dig Dis Sci. 2012;57:3042–4.
Article
PubMed
Google Scholar
M’Koma AE. Inflammatory bowel disease: an expanding global health problem. Clin Med Insights Gastroenterol. 2013;6:33–47.
PubMed
PubMed Central
Google Scholar
Cars T, Wettermark B, Löfberg R, Eriksson I, Sundström J, Lördal M. Healthcare utilisation and drug treatment in a large cohort of patients with inflammatory bowel disease. J Crohn’s Colitis. 2016;10:556–65.
Article
Google Scholar
Danese S, Bonovas S, Peyrin-Biroulet L. Biosimilars in IBD: from theory to practice. Nat Rev Gastroenterol Hepatol. 2017;14:22–31.
Article
PubMed
Google Scholar
Saudi Vision 2030. https://vision2030.gov.sa/en. Accessed 22 Apr 2019.
Al-Sharqi OZ, Abdullah MT. Diagnosing Saudi health reforms: is NHIS the right prescription? Int J Health Plann Manage. 2013;28:308–19.
Article
PubMed
Google Scholar
Al-Hanawi MK, Alsharqi O, Almazrou S, Vaidya K. Healthcare finance in the Kingdom of Saudi Arabia: a qualitative study of householders’ attitudes. Appl Health Econ Health Policy. 2018;16:55–64.
Article
PubMed
Google Scholar
Lichtenstein GR. Introduction to biosimilar use in patients with inflammatory bowel disease. Gastroenterol Hepatol. 2017;13:612–4.
Google Scholar
Al-Hanawi MK, Khan SA, Al-Borie HM. Healthcare human resource development in Saudi Arabia: emerging challenges and opportunities-a critical review. Public Health Rev. 2019;40:1.
Article
PubMed
PubMed Central
Google Scholar
Ha C, Katz S. Management of inflammatory bowel disease in the elderly: do biologicals offer a better alternative? Drugs Aging. 2013;30:871–6.
Article
PubMed
Google Scholar
Pillai N, Dusheiko M, Burnand B, Pittet V. A systematic review of cost-effectiveness studies comparing conventional, biological and surgical interventions for inflammatory bowel disease. PLoS ONE. 2017;12:e0185500.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wong DJ, Roth EM, Feuerstein JD, Poylin VY. Surgery in the age of biologics. Gastroenterol Rep. 2019;7:77–90.
Article
Google Scholar
Singh S, Facciorusso A, Dulai PS, Jairath V, Sandborn WJ. Comparative risk of serious infections with biologic and/or immunosuppressive therapy in patients with inflammatory bowel diseases: a systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2019. https://doi.org/10.1016/j.cgh.2019.02.044 (Epub ahead of print).
Article
PubMed
PubMed Central
Google Scholar