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  1. Content type: Research

    Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally. In China, sorafenib and oxaliplatin plus infusional-fluorouracil/leucovorin (FOLFOX4) are approved for the systemic treatmen...

    Authors: Shukui Qin, Eliza Kruger, Seng Chuen Tan, Shuqun Cheng, Nanya Wang and Jun Liang

    Citation: Cost Effectiveness and Resource Allocation 2018 16:29

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  2. Content type: Research

    Human monoclonal antibody ustekinumab is a novel Crohn’s disease (CD) treatment blocking pro-inflammatory cytokines interleukin-12 and 23. The study’s objective was to assess cost-effectiveness of ustekinumab ...

    Authors: Amanda Hansson-Hedblom, Chrissy Almond, Fredrik Borgström, Indeg Sly, Dana Enkusson, Anders Troelsgaard Buchholt and Linda Karlsson

    Citation: Cost Effectiveness and Resource Allocation 2018 16:28

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  3. Content type: Research

    Evidence on the relative costs and effects of interventions that do not consider ‘real-world’ constraints on implementation may be misleading. However, in many low- and middle-income countries, time and data s...

    Authors: Fiammetta M. Bozzani, Don Mudzengi, Tom Sumner, Gabriela B. Gomez, Piotr Hippner, Vicky Cardenas, Salome Charalambous, Richard White and Anna Vassall

    Citation: Cost Effectiveness and Resource Allocation 2018 16:27

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  4. Content type: Research

    The current health system reforms in Kosovo aim to improve health status through universal health coverage. Risk pooling and ensuring access to necessary care without financial hardship are envisaged through c...

    Authors: Fatime Arenliu Qosaj, Guenter Froeschl, Merita Berisha, Bashkim Bellaqa and Rolf Holle

    Citation: Cost Effectiveness and Resource Allocation 2018 16:26

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  5. Content type: Research

    A variety of mobile-based health technologies (mHealth) have been developed for use by community health workers to augment their performance. One such mHealth intervention—ReMiND program, was implemented in a ...

    Authors: Shankar Prinja, Pankaj Bahuguna, Aditi Gupta, Ruby Nimesh, Madhu Gupta and Jarnail Singh Thakur

    Citation: Cost Effectiveness and Resource Allocation 2018 16:25

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  6. Content type: Research

    There are limited data describing the cost-effectiveness of brief interventions for substance use in resource-poor settings. Using a patient and provider perspective, this study investigates the cost-effective...

    Authors: Rebecca Dwommoh, Katherine Sorsdahl, Bronwyn Myers, Kwaku Poku Asante, Tracey Naledi, Dan J. Stein and Susan Cleary

    Citation: Cost Effectiveness and Resource Allocation 2018 16:24

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  7. Content type: Methodology

    Translating prognostic and diagnostic biomarker candidates into clinical applications takes time, is very costly, and many candidates fail. It is therefore crucial to be able to select those biomarker candidat...

    Authors: Gimon de Graaf, Douwe Postmus, Jan Westerink and Erik Buskens

    Citation: Cost Effectiveness and Resource Allocation 2018 16:23

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  8. Content type: Research

    Previous studies have showed that the early diagnosis of threatened preterm labor decreases neonatal morbidity and mortality, avoids maternal morbidity induced by antepartum bed rest and unnecessary treatment,...

    Authors: Thomas Desplanches, Catherine Lejeune, Jonathan Cottenet, Paul Sagot and Catherine Quantin

    Citation: Cost Effectiveness and Resource Allocation 2018 16:21

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  9. Content type: Review

    Cardiovascular disease (CVD) is the leading cause of deaths globally, with greatest premature mortality in the low- and middle-income countries (LMIC). Many of these countries, especially in sub-Saharan Africa...

    Authors: Leopold Ndemnge Aminde, Noah Fongwen Takah, Belen Zapata-Diomedi and J. Lennert Veerman

    Citation: Cost Effectiveness and Resource Allocation 2018 16:22

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  10. Content type: Research

    Colorectal cancer is one of the most common cancers worldwide and is associated with high mortality when detected at a later stage. There is a paucity of studies from low and middle income countries to support...

    Authors: Nelya Melnitchouk, Djøra I. Soeteman, Jennifer S. Davids, Adam Fields, Joshua Cohen, Farzad Noubary, Andrey Lukashenko, Olena O. Kolesnik and Karen M. Freund

    Citation: Cost Effectiveness and Resource Allocation 2018 16:20

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  11. Content type: Methodology

    Health-care utilities differ considerably from country to country. Our objective was to examine the association of cultural values based on Hofstede’s cultural dimensions’ theory with utility values that were ...

    Authors: Jörg Mahlich, Piyameth Dilokthornsakul, Rosarin Sruamsiri and Nathorn Chaiyakunapruk

    Citation: Cost Effectiveness and Resource Allocation 2018 16:19

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  12. Content type: Review

    Cost-effectiveness analysis (CEA) is frequently used as an input for guiding priority setting in health. However, CEA seldom incorporates information about trade-offs between total health gains and equity impa...

    Authors: Marie-Anne Boujaoude, Andrew J. Mirelman, Kim Dalziel and Natalie Carvalho

    Citation: Cost Effectiveness and Resource Allocation 2018 16:18

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  13. Content type: Research

    Cost-effectiveness of once-daily umeclidinium bromide (UMEC) was compared with once-daily tiotropium (TIO) and once-daily glycopyrronium (GLY) in patients with chronic obstructive pulmonary disease (COPD) from...

    Authors: Dhvani Shah, Maurice Driessen, Nancy Risebrough, Timothy Baker, Ian Naya, Andrew Briggs and Afisi S. Ismaila

    Citation: Cost Effectiveness and Resource Allocation 2018 16:17

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  14. Content type: Review

    In the light of demographic developments health promotion interventions for older people are gaining importance. In addition to methodological challenges arising from the economic evaluation of health promotio...

    Authors: Kai Huter, Katarzyna Dubas-Jakóbczyk, Ewa Kocot, Katarzyna Kissimova-Skarbek and Heinz Rothgang

    Citation: Cost Effectiveness and Resource Allocation 2018 16:14

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  15. Content type: Research

    Fenestrated endovascular aneurysm repair (fEVAR) is a new approach for complex abdominal aortic aneurysms, limited to a few specialist centers, with limited evidence base. We developed a cost-effectiveness dec...

    Authors: Oriana Ciani, David Epstein, Claire Rothery, Rod S. Taylor and Mark Sculpher

    Citation: Cost Effectiveness and Resource Allocation 2018 16:15

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  16. Content type: Research

    This study assessed the costs and cost-efficiency of a mobile cash transfer implemented in Tapoa Province, Burkina Faso in the MAM’Out randomized controlled trial from June 2013 to December 2014, using mixed m...

    Authors: Chloe Puett, Cécile Salpéteur, Freddy Houngbe, Karen Martínez, Dieynaba S. N’Diaye and Audrey Tonguet-Papucci

    Citation: Cost Effectiveness and Resource Allocation 2018 16:13

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  17. Content type: Research

    This study aims to assess the cost-effectiveness of early physician consultation and guideline-based intervention to prevent endometriosis and/or disease progression using oral contraceptive (OC) and progestin...

    Authors: Ichiro Arakawa, Mikio Momoeda, Yutaka Osuga, Ikuko Ota and Kaori Koga

    Citation: Cost Effectiveness and Resource Allocation 2018 16:12

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  18. Content type: Research

    Human resources are consistently cited as a leading contributor to health care costs; however the availability of internationally comparable data on health worker earnings for all countries is a challenge for ...

    Authors: Juliana Serje, Melanie Y. Bertram, Callum Brindley and Jeremy A. Lauer

    Citation: Cost Effectiveness and Resource Allocation 2018 16:10

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  19. Content type: Research

    The objective of this work is to estimate the financial impact of increasing the monitoring period for breast cancer, which is financed by the Sistema de Protección Social en Salud (SPSS—Social Protection Syst...

    Authors: Román Rodríguez-Aguilar, José Antonio Marmolejo-Saucedo and Sonia Tavera-Martínez

    Citation: Cost Effectiveness and Resource Allocation 2018 16:9

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  20. Content type: Research

    High pharmaceutical expenditure is one of the main concerns for policymakers worldwide. In Colombia, a middle-income country, outpatient prescription represents over 10% of total health expenditure in the mand...

    Authors: Sergio I. Prada, Victoria E. Soto, Tatiana S. Andia, Claudia P. Vaca, Álvaro A. Morales, Sergio R. Márquez and Alejandro Gaviria

    Citation: Cost Effectiveness and Resource Allocation 2018 16:8

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  21. Content type: Methodology

    Many economic evaluations ignore economies of scale in their cost estimation, which means that cost parameters are assumed to have a linear relationship with the level of production. Economies of scale is the ...

    Authors: Thanthima Suwanthawornkul, Naiyana Praditsitthikorn, Wantanee Kulpeng, Manuel Alexander Haasis, Anna Melissa Guerrero and Yot Teerawattananon

    Citation: Cost Effectiveness and Resource Allocation 2018 16:7

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  22. Content type: Research

    In Korea, hepatitis B virus (HBV) infection accounts for approximately 65–75% of HBV-related diseases, such as chronic hepatitis and liver cancer, and mother-to-child transmission is presumed to be a major sou...

    Authors: Donghoon Lee, Hyun-Young Shin and Sang Min Park

    Citation: Cost Effectiveness and Resource Allocation 2018 16:6

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  23. Content type: Research

    All health care systems in the world struggle with rising costs for drugs. We sought to explore factors impacting on prescribing costs in a nationwide database of ambulatory care in Germany. Factors identified...

    Authors: O. Hirsch, M. Schulz, M. Erhart and N. Donner-Banzhoff

    Citation: Cost Effectiveness and Resource Allocation 2018 16:5

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  24. Content type: Research

    Use of malaria rapid diagnostic test (mRDT) enhances patient management and reduces costs associated with the inappropriate use of antimalarials. Despite its proven clinical effectiveness, mRDT is not readily ...

    Authors: Theresa Tawiah, Keziah Malam, Anthony Kwarteng, Constance Bart-Plange, Lawrence Febir, Vivian Aubyn, Konrad Obermann, Seth Owusu-Agyei and Kwaku Poku Asante

    Citation: Cost Effectiveness and Resource Allocation 2018 16:4

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  25. Content type: Research

    A significant minority of asthma patients remain uncontrolled despite the use of inhaled corticosteroids (ICS) and long-acting beta-agonists (LABA). A number of add-on therapies, including monoclonal antibodie...

    Authors: Zafar Zafari, Mohsen Sadatsafavi and J. Mark FitzGerald

    Citation: Cost Effectiveness and Resource Allocation 2018 16:3

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  26. Content type: Review

    Due to its epidemiological relevance, several studies have been performed to assess the cost-effectiveness of diagnostic tests and treatments in colorectal cancer (CRC) patients.

    Authors: Annamaria Guglielmo, Nicoletta Staropoli, Monica Giancotti and Marianna Mauro

    Citation: Cost Effectiveness and Resource Allocation 2018 16:2

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  27. Content type: Research

    The overuse of antibiotics has been identified as a major challenge in regard to the rational prescription of medicines in low and middle income countries. Extensive studies on the effectiveness of persuasive ...

    Authors: Yuqing Tang, Chaojie Liu, Zinan Zhang and Xinping Zhang

    Citation: Cost Effectiveness and Resource Allocation 2018 16:1

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  28. Content type: Research

    To date no one has examined the quality of life and direct costs of care in treating early stage breast cancer with adjunct intraoperative radiation therapy (IORT) versus external beam radiation therapy (EBRT)...

    Authors: Rakesh Patel, Olga Ivanov and Jeff Voigt

    Citation: Cost Effectiveness and Resource Allocation 2017 15:22

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  29. Content type: Methodology

    Estimating health care costs, either in the context of understanding resource utilization in the implementation of a health plan, or in the context of economic evaluation, has become a common activity of healt...

    Authors: Melanie Y. Bertram, Karin Stenberg, Callum Brindley, Jina Li, Juliana Serje, Rory Watts and Tessa Tan-Torres Edejer

    Citation: Cost Effectiveness and Resource Allocation 2017 15:21

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  30. Content type: Research

    Anti-tumor necrosis factor (anti-TNF) agents are an effective, but costly, treatment for spondyloarthritis (SpA). Worldwide, multiple sets of access criteria aim to restrict anti-TNF therapy to patients with s...

    Authors: Stephanie Harvard, Daphne Guh, Nick Bansback, Pascal Richette, Alain Saraux, Bruno Fautrel and Aslam Anis

    Citation: Cost Effectiveness and Resource Allocation 2017 15:20

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  31. Content type: Research

    This study was designed to assess the cost-effectiveness of vildagliptin versus glimepiride as add-on to metformin in the management of type 2 diabetes mellitus (T2DM) patients in the Greek healthcare setting.

    Authors: Hara Kousoulakou, Magdalini Hatzikou, Varvara Baroutsou and John Yfantopoulos

    Citation: Cost Effectiveness and Resource Allocation 2017 15:19

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  32. Content type: Research

    The aim of this study was to assess the cost-effectiveness of human papillomavirus (HPV) vaccination in addition to the current cervical cancer screening programme in Germany using a dynamic transmission model.

    Authors: Oliver Damm, Johannes Horn, Rafael T. Mikolajczyk, Mirjam E. E. Kretzschmar, Andreas M. Kaufmann, Yvonne Deleré, Bernhard Ultsch, Ole Wichmann, Alexander Krämer and Wolfgang Greiner

    Citation: Cost Effectiveness and Resource Allocation 2017 15:18

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  33. Content type: Research

    Currently, two pediatric pneumococcal conjugate vaccines are available in the private market of Malaysia—13-valent pneumococcal conjugate vaccine (PCV13) and pneumococcal polysaccharide and non-typeable Haemophil...

    Authors: Xiao Jun Wang, Ashwini Saha and Xu-Hao Zhang

    Citation: Cost Effectiveness and Resource Allocation 2017 15:17

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  34. Content type: Research

    In countries such as Cyprus the financial crisis and the recession have severely affected the funding and priority setting of the health care system. There is evidence highlighting the importance of population...

    Authors: Antonis Farmakas, Mamas Theodorou, Petros Galanis, Georgios Karayiannis, Stefanos Ghobrial, Nikos Polyzos, Evridiki Papastavrou, Eirini Agapidaki and Kyriakos Souliotis

    Citation: Cost Effectiveness and Resource Allocation 2017 15:16

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  35. Content type: Research

    As treatments for chronic hepatitis C are moving away from interferon-containing regimens, the most appropriate allocation of resources to higher cost, interferon-free, direct-acting antiviral (DAA) regimens n...

    Authors: Phil McEwan, Samantha Webster, Thomas Ward, Michael Brenner, Anupama Kalsekar and Yong Yuan

    Citation: Cost Effectiveness and Resource Allocation 2017 15:15

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  36. Content type: Research

    In 2013, 78% of malaria deaths occurred in children aged 5 years and below, in sub-Saharan Africa. Treatment of severe malaria requires a health facility with inpatient care. However, in most sub-Sahara Africa...

    Authors: Vivian Rakuomi, Faith Okalebo, Stanley Ndwigah and Levi Mbugua

    Citation: Cost Effectiveness and Resource Allocation 2017 15:14

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  37. Content type: Research

    This study evaluated the potential cost-effectiveness of cervical cancer screening in HIV treatment clinics in Nairobi, Kenya.

    Authors: Marita R. Zimmermann, Elisabeth Vodicka, Joseph B. Babigumira, Timothy Okech, Nelly Mugo, Samah Sakr, Louis P. Garrison and Michael H. Chung

    Citation: Cost Effectiveness and Resource Allocation 2017 15:13

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  38. Content type: Research

    Innovations that improve the affordability, accessibility, or effectiveness of health care played a major role in the Millennium Development Goal achievements and will be critical for reaching the ambitious ne...

    Authors: Tara Herrick, Claudia Harner-Jay, Craig Shaffer, Greg Zwisler, Peder Digre and Amie Batson

    Citation: Cost Effectiveness and Resource Allocation 2017 15:12

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  39. Content type: Research

    In Italy HPV vaccination with the quadrivalent vaccine (Gardasil®) is offered actively and free of charge to girls aged 12 since 2007. A nine-valent vaccine (Gardasil 9®) received the European market authorizatio...

    Authors: Francesco Saverio Mennini, Paolo Bonanni, Florence Bianic, Chiara de Waure, Gianluca Baio, Giacomo Plazzotta, Mathieu Uhart, Alessandro Rinaldi and Nathalie Largeron

    Citation: Cost Effectiveness and Resource Allocation 2017 15:11

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  40. Content type: Review

    Malaria continues to be a public health problem despite past and on-going control efforts. For sustenance of control efforts to achieve the malaria elimination goal, it is important that the most cost-effectiv...

    Authors: Resign Gunda and Moses John Chimbari

    Citation: Cost Effectiveness and Resource Allocation 2017 15:10

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  41. Content type: Research

    This study evaluates the cost-effectiveness of the DAZT program for scaling up treatment of acute child diarrhea in Gujarat India using a net-benefit regression framework.

    Authors: Samuel D. Shillcutt, Amnesty E. LeFevre, Christa L. Fischer-Walker, Sunita Taneja, Robert E. Black and Sarmila Mazumder

    Citation: Cost Effectiveness and Resource Allocation 2017 15:9

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  42. Content type: Methodology

    Ofatumumab (Arzerra®, Novartis) is a treatment for chronic lymphocytic leukemia refractory to fludarabine and alemtuzumab [double refractory (DR-CLL)]. Ofatumumab was licensed on the basis of an uncontrolled Phas...

    Authors: Anthony J. Hatswell, Gwilym J. Thompson, Penny A. Maroudas, Oleg Sofrygin and Thomas E. Delea

    Citation: Cost Effectiveness and Resource Allocation 2017 15:8

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  43. Content type: Review

    This study aims to summarise and describe the evolution of published economic evaluations of vaccines in Canada, thereby outlining the current state of this expanding and meaningful research.

    Authors: Ellen R. S. Rafferty, Heather L. Gagnon, Marwa Farag and Cheryl L. Waldner

    Citation: Cost Effectiveness and Resource Allocation 2017 15:7

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  44. Content type: Research

    This study is an initial effort to examine the dynamics of efficiency and productivity in Greek public hospitals during the first phase of the crisis 2009–2012. Data were collected by the Ministry of Health af...

    Authors: P. Xenos, J. Yfantopoulos, M. Nektarios, N. Polyzos, P. Tinios and A. Constantopoulos

    Citation: Cost Effectiveness and Resource Allocation 2017 15:6

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  45. Content type: Methodology

    Mobile and wireless technology for health (mHealth) has the potential to improve health outcomes by addressing critical health systems constraints that impede coverage, utilization, and effectiveness of health...

    Authors: Amnesty E. LeFevre, Samuel D. Shillcutt, Sean Broomhead, Alain B. Labrique and Tom Jones

    Citation: Cost Effectiveness and Resource Allocation 2017 15:5

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  46. Content type: Research

    In resource-limited settings with a high prevalence of human immunodeficiency virus (HIV) infection such as Zambia, decentralization of HIV/acquired immunodeficiency syndrome (HIV/AIDS) treatment and care with...

    Authors: Shinsuke Miyano, Gardner Syakantu, Kenichi Komada, Hiroyoshi Endo and Tomohiko Sugishita

    Citation: Cost Effectiveness and Resource Allocation 2017 15:4

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  47. Content type: Research

    Health care systems around the world have started to develop pharmacists prescribing for minor ailments (PPMA) programs. These programs aim to improve the efficiency of care, reduce physician visits, and incre...

    Authors: Ellen Rafferty, Mohsen Yaghoubi, Jeff Taylor and Marwa Farag

    Citation: Cost Effectiveness and Resource Allocation 2017 15:3

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  48. Content type: Research

    Neonatal mortality remains unacceptably high in many low and middle-income countries, including India. A community mobilisation intervention using participatory learning and action with women’s groups facilita...

    Authors: Rajesh Kumar Sinha, Hassan Haghparast-Bidgoli, Prasanta Kishore Tripathy, Nirmala Nair, Rajkumar Gope, Shibanand Rath and Audrey Prost

    Citation: Cost Effectiveness and Resource Allocation 2017 15:2

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