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Table 5 Other parameters incorporated in the model

From: Modeling the Cost-effectiveness of Esophageal Cancer Screening in China

Parameter

Input

SA range

Distribution

References

Transition probability

 Normal to LGIN

0.0000

–

–

–

 LGIN to normal

0.1427

0.1142–0.1712

Beta

[32,33,34,35,36,37,38]

 IC to DFS_IC

0.9363-d_nor

0.7490–0.9363

Beta

[17]

 IC progress

0.0534

0.0427–0.0641

Beta

[17, 47,48,49]

 SM proportion

0.2143

0.1714–0.2572

Dirichlet

Screening

 Mod proportion

0.5714

0.4571–0.6857

Dirichlet

 

 Adv proportion

0.2143

0.1714–0.2572

Dirichlet

 

 DFS_IC to IC

0.0069

0.0055–0.0083

Beta

[50]

 DFS_IC progress

0.0268

0.0214–0.0322

Beta

[51]

 SM proportion

0.5556

0.4445–0.6667

Dirichlet

[51]

 Mod proportion

0.4444

0.3555–0.5333

Dirichlet

[51]

 Adv proportion

0.0000

0.0000–0.0000

Dirichlet

[51]

 SM to DFS_SM

0.9051-d_nor

0.7241–1.0000

Beta

[52]

 SM progress

0.1386

0.1109–0.1663

Beta

[53, 54]

 Mod proportion

0.7562

0.6050–0.9074

Beta

[48, 55,56,57,58,59,60,61]

 Adv proportion

0.2438

0.1950–0.2926

Beta

[48, 55,56,57,58,59,60,61]

 DFS_SM to SM

0.0393

0.0314–0.0472

Beta

[62]

 DFS_SM progress

0.0883

0.0706–0.1060

Beta

[53]

 Mod proportion

0.7562

0.6050–0.9074

Beta

[48, 55,56,57,58,59,60,61]

 Adv proportion

0.2438

0.1950–0.2926

Beta

[48, 55,56,57,58,59,60,61]

 Mod to DFS_Mod

0.5930-d_nor

0.4744–0.7116

Beta

[63]

 Mod to Adv

0.0317

0.0254–0.0380

Beta

[64]

 DFS_Mod to Mod

0.0425

0.0340–0.0510

Dirichlet

[64]

 DFS_Mod to Adv

0.0097

0.0078–0.0116

Dirichlet

[64]

 Adv to PFS

0.1967-d_nor

0.1574–0.2360

Dirichlet

[65]

 PFS progress

0.7002

0.5602–0.8402

Dirichlet

[66]

 RR

0.7000

0.5600–0.8400

Lognormal

[15]

EC state-specific death probability (age ≤ 65 years)

 SM

0.0994

0.0795–0.1193

Beta

[67]

 DFS_SM

0.0633

0.0506–0.0760

Beta

[67]

 Mod

0.2988

0.2390–0.3586

Beta

[54]

 DFS_Mod

0.1902

0.1522–0.2282

Beta

[54]

 Adv

0.4613

0.3690–0.5536

Beta

[66, 68]

 PFS

0.4303

0.3442–0.5164

Beta

[66, 68]

Risk ratios of EC death probability among patients aged more than 65 years compared to patients aged less than 65 years

 RR_SM/RR_DFS_SM

1.30

1.20–1.50

Lognormal

[69]

 RR_Mod/RR_DFS_Mod

1.20

1.10–1.30

Lognormal

[69]

 RR_Adv/RR_PFS_Adv

1.16

1.10–1.20

Lognormal

[69]

  1. SA one-way sensitivity analysis, d_nor annual death probability for health individuals, which was defined as the difference between all-cause mortality and EC-related mortality
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Cost Effectiveness and Resource Allocation

ISSN: 1478-7547

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