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Table 5 Other parameters incorporated in the model

From: Modeling the Cost-effectiveness of Esophageal Cancer Screening in China

Parameter Input SA range Distribution References
Transition probability
 Normal to LGIN 0.0000
 LGIN to normal 0.1427 0.1142–0.1712 Beta [32,33,34,35,36,37,38]
 IC to DFS_IC 0.9363-d_nor 0.7490–0.9363 Beta [17]
 IC progress 0.0534 0.0427–0.0641 Beta [17, 47,48,49]
 SM proportion 0.2143 0.1714–0.2572 Dirichlet Screening
 Mod proportion 0.5714 0.4571–0.6857 Dirichlet  
 Adv proportion 0.2143 0.1714–0.2572 Dirichlet  
 DFS_IC to IC 0.0069 0.0055–0.0083 Beta [50]
 DFS_IC progress 0.0268 0.0214–0.0322 Beta [51]
 SM proportion 0.5556 0.4445–0.6667 Dirichlet [51]
 Mod proportion 0.4444 0.3555–0.5333 Dirichlet [51]
 Adv proportion 0.0000 0.0000–0.0000 Dirichlet [51]
 SM to DFS_SM 0.9051-d_nor 0.7241–1.0000 Beta [52]
 SM progress 0.1386 0.1109–0.1663 Beta [53, 54]
 Mod proportion 0.7562 0.6050–0.9074 Beta [48, 55,56,57,58,59,60,61]
 Adv proportion 0.2438 0.1950–0.2926 Beta [48, 55,56,57,58,59,60,61]
 DFS_SM to SM 0.0393 0.0314–0.0472 Beta [62]
 DFS_SM progress 0.0883 0.0706–0.1060 Beta [53]
 Mod proportion 0.7562 0.6050–0.9074 Beta [48, 55,56,57,58,59,60,61]
 Adv proportion 0.2438 0.1950–0.2926 Beta [48, 55,56,57,58,59,60,61]
 Mod to DFS_Mod 0.5930-d_nor 0.4744–0.7116 Beta [63]
 Mod to Adv 0.0317 0.0254–0.0380 Beta [64]
 DFS_Mod to Mod 0.0425 0.0340–0.0510 Dirichlet [64]
 DFS_Mod to Adv 0.0097 0.0078–0.0116 Dirichlet [64]
 Adv to PFS 0.1967-d_nor 0.1574–0.2360 Dirichlet [65]
 PFS progress 0.7002 0.5602–0.8402 Dirichlet [66]
 RR 0.7000 0.5600–0.8400 Lognormal [15]
EC state-specific death probability (age ≤ 65 years)
 SM 0.0994 0.0795–0.1193 Beta [67]
 DFS_SM 0.0633 0.0506–0.0760 Beta [67]
 Mod 0.2988 0.2390–0.3586 Beta [54]
 DFS_Mod 0.1902 0.1522–0.2282 Beta [54]
 Adv 0.4613 0.3690–0.5536 Beta [66, 68]
 PFS 0.4303 0.3442–0.5164 Beta [66, 68]
Risk ratios of EC death probability among patients aged more than 65 years compared to patients aged less than 65 years
 RR_SM/RR_DFS_SM 1.30 1.20–1.50 Lognormal [69]
 RR_Mod/RR_DFS_Mod 1.20 1.10–1.30 Lognormal [69]
 RR_Adv/RR_PFS_Adv 1.16 1.10–1.20 Lognormal [69]
  1. SA one-way sensitivity analysis, d_nor annual death probability for health individuals, which was defined as the difference between all-cause mortality and EC-related mortality
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