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Table 2 Cost estimates ($)

From: A cost-effectiveness analysis of the combination of serplulimab with chemotherapy for advanced esophageal squamous cell carcinoma: insights from the ASTRUM-007 trial

Parameters

Baseline value

Range

Reference

Distribution

Minimum

Maximum

Drug cost, $/per cycle

Serplulimab

198

158

238

Real-world

Gamma

Cisplatin

12

10

14

Real-world

Gamma

5-fluorouracil

127

102

152

Real-world

Gamma

Paclitaxel

180

144

216

Real-world

Gamma

Cost of AEs

Serplulimab plus CF

65

52

78

(21, 28, 29)

Gamma

CF

60

48

72

(21, 28, 29)

Gamma

Laboratory per cycle

53

42

64

(21)

Gamma

Tumor imaging per cycle

162

130

194

(21)

Gamma

Administration per cycle

12

10

14

(21)

Gamma

PD-L1 test per patient

86

69

103

Real-world

Gamma

Best supportive care per cycle

70

56

84

(21)

Gamma

Terminal care per patient

1,402

1,122

1,682

(27)

Gamma

  1. Abbreviation: AEs, adverse events; CF, cisplatin and 5-fluorouracil; PD-L1, programmed death ligand 1