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Table 2 Base-case cost-effectiveness results from the Chinese healthcare perspective

From: Methodology and results of cost-effectiveness of LDL-C lowering with evolocumab in patients with acute myocardial infarction in China

 

Cost, CNY

QALY

ICER, CNY

Total

Incremental

Total

Incremental

PEACE

     

 Statins

299509.17

NA

8.19

NA

NA

 Statins + Evo 140mgQ2W

348242.12

48732.96

8.54

0.35

137755.18

 Statins + Evo 420mgQM

375490.01

75980.84

8.54

0.35

214777.76

BERSONa

     

 Statins

279123.88

NA

9.64

NA

NA

 Statins + Evo 140mgQ2W

330152.91

51029.03

10.18

0.54

94869.54

 Statins + Evo 420mgQM

365284.28

86160.40

10.13

0.49

177450.90

SuValue®, LDL-C ≥ 100 mg/dl

     

 Statins

300258.69

NA

8.33

NA

NA

 Statins + Evo 140mgQ2W

324484.37

24225.68

8.92

0.59

40905.80

 Statins + Evo 420mgQM

353686.48

53427.79

8.92

0.59

90214.47

SuValue®, LDL-C ≥ 70 mg/dl

     

 Statins

284482.16

NA

8.39

NA

NA

 Statins + Evo 140mgQ2W

318921.61

34439.45

8.86

0.48

72449.95

 Statins + Evo 420mgQM

347889.94

63407.78

8.86

0.48

133390.36

  1. CNY, Chinese Yuan; Evo 140mgQ2W, evolocumab 140 mg every 2 weeks; Evo 420mgQM, evolocumab 420 mg monthly; LDL-C, low-density lipoprotein cholesterol; MI, myocardial infarction; NA, not applicable
  2. a: The background statin in the BERSON study was atorvastatin 20 mg/d