Table 1 The five clinical trials (A and B are the same trial but assessed two separate treatment regimens and thus are included separately), the data corresponding to the criteria of interest and their final calculated aggregate value
Trial | Unmet need | Size of target population | Access to trials | Patient outcomes | Total trial cost | Academic impact | Use of trial results | Aggregate value |
|---|---|---|---|---|---|---|---|---|
Example A (Hammel et al., 2016) [29] | 8.0 | 12.0 | 55.0 | 1.3 | 40.5 | 440.0 | Informed research | 45.81 |
Example B (Hammel et al., 2016) [29] | 8.0 | 222.0 | 55.0 | 1.7 | 55.0 | 440.0 | Granted regulatory approval | 57.31 |
Example C (Rombouts et al., 2016) [30] | 35.0 | 12.0 | 55.0 | 14.8 | 13.0 | 31.0 | Informed policy | 51.83 |
Example D (Yang et al., 2011) [31] | 32.0 | 8.1 | 55.0 | 4.5 | 40.5 | 508.0 | Informed research | 40.61 |
Example E (Sledge et al., 2020) [32] | 91.0 | 65.0 | 55.0 | 9.4 | 27.0 | 69.0 | Unused | 24.31 |
Example F (Shroff., 2019) [33] | 24.0 | 7.8 | 55.0 | 7.5 | 40.5 | 40.0 | Unused | 32.19 |