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Table 1 Scope of the economic analysis

From: Cost-utility analysis of genomic profiling in early breast cancer in Colombia

Element economic analysis

Description

Population

Women with HR + and HER2– early-stage breast cancer (LN0) with high-risk clinical criteria as per the MINDACT trial [19]

Interventions

1→Oncotype DX (cutoff points as per the TAILORx trial) [23]

2→Mammaprint (cutoff points as per the MINDACT trial) [19]

Comparator

Chemotherapy for all

Primary health economic outcome

Incremental cost per QALY gained and net monetary benefit

Perspective

Colombian NHS

Time horizon

5 years

Discount rate

5% per annum. A sensitivity analysis was performed with discount rates of 0%, 3.5%, and 7% [24]

Price year

2021

  1. NHS National Health System, HR +  HR-positive, HER2 −  HER2-negative, LN0 without lymph node involvement, QALY quality-adjusted life-years