Table 1 The DOT assignment and multiple replacement sampling results
Sampling number | Patient number from reconstructed IPD | PFS time | PFS censoring | OS time | OS censoring | PD time | Randomized start time of receiving treatment | Date of the end of year | Residual months in the first year | DOT of intervention in the 1st year | DOT of subsequent treatment in the 1st year | DOT of intervention in the 2nd year | DOT of subsequent treatment in the 2nd year | DOT of intervention in the 3rd year | DOT of subsequent treatment in the 3rd year | DOT of intervention in the 4th year | DOT of subsequent treatment in the 4th year |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 114 | 260.74 | 1 | 287.82 | 1 | 27.08 | 01/06 | 12/31 | 11.97 | 11.97 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
2 | 12 | 1.08 | 1 | 2.89 | 1 | 1.81 | 08/26 | 12/31 | 4.23 | 1.08 | 1.81 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
3 | 142 | 378.10 | 1 | 402.66 | 1 | 24.56 | 05/17 | 12/31 | 7.60 | 7.60 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
4 | 117 | 278.79 | 1 | 298.66 | 1 | 19.86 | 02/01 | 12/31 | 11.10 | 11.10 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
5 | 11 | 1.08 | 1 | 2.53 | 1 | 1.44 | 07/24 | 12/31 | 5.33 | 1.08 | 1.44 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
6 | 150 | 442.39 | 1 | 459.36 | 1 | 16.97 | 02/13 | 12/31 | 10.70 | 10.70 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
7 | 109 | 230.04 | 1 | 270.13 | 1 | 40.09 | 01/20 | 12/31 | 11.50 | 11.50 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
8 | 133 | 353.19 | 1 | 362.22 | 1 | 9.03 | 12/22 | 12/31 | 0.30 | 0.30 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
9 | 145 | 399.41 | 1 | 417.11 | 1 | 17.70 | 03/22 | 12/31 | 9.47 | 9.47 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
10 | 144 | 392.91 | 1 | 412.05 | 1 | 19.14 | 05/12 | 12/31 | 7.77 | 7.77 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
11 | 150 | 442.39 | 1 | 459.36 | 1 | 16.97 | 02/13 | 12/31 | 10.70 | 10.70 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
12 | 19 | 1.81 | 1 | 4.69 | 1 | 2.89 | 01/28 | 12/31 | 11.23 | 1.81 | 2.89 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
13 | 82 | 15.89 | 1 | 123.51 | 1 | 107.62 | 03/17 | 12/31 | 9.63 | 9.63 | 0.00 | 6.26 | 5.74 | 0.00 | 12.00 | 0.00 | 12.00 |
14 | 112 | 248.82 | 1 | 282.77 | 1 | 33.95 | 06/27 | 12/31 | 6.23 | 6.23 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 | 12.00 | 0.00 |
15 | 11 | 1.08 | 1 | 2.53 | 1 | 1.44 | 07/24 | 12/31 | 5.33 | 1.08 | 1.44 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
… | … | … | … | … | … | … | … | … | … | … | … | … | … | … | … | … | … |
996 | 19 | 1.81 | 1 | 4.69 | 1 | 2.89 | 01/28 | 12/31 | 11.23 | 1.81 | 2.89 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
997 | 80 | 14.45 | 1 | 112.67 | 1 | 98.23 | 11/29 | 12/31 | 1.07 | 1.07 | 0.00 | 12.00 | 0.00 | 1.38 | 10.62 | 0.00 | 12.00 |
998 | 88 | 24.92 | 1 | 159.62 | 1 | 134.70 | 02/03 | 12/31 | 11.03 | 11.03 | 0.00 | 12.00 | 0.00 | 1.88 | 10.12 | 0.00 | 12.00 |
999 | 41 | 3.97 | 1 | 15.17 | 1 | 11.20 | 12/29 | 12/31 | 0.07 | 0.07 | 0.00 | 3.91 | 8.09 | 0.00 | 3.10 | 0.00 | 0.00 |
1000 | 13 | 1.44 | 1 | 3.25 | 1 | 1.81 | 12/06 | 12/31 | 0.83 | 0.83 | 0.00 | 0.61 | 1.81 | 0.00 | 0.00 | 0.00 | 0.00 |
Average | 4.90 | 0.75 | 6.60 | 2.84 | 5.24 | 2.99 | 5.06 | 2.5 |