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Table 3 Main cost-effectiveness results in the seven countries

From: Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: an analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru

Strategy

Outcome/country

Argentina

Brazil

Chile

Colombia

Costa Rica

México

Perú

No vaccination

Costs

$ 2,489,103,233

$ 14,899,414,477

$ 1,426,693,488

$ 5,213,429,639

$ 1,000,387,362

$ 24,460,665,837

$ 3,290,563,102

QALYs lost*

1,678,317

3,650,818

423,399

1,878,855

130,323

4,304,472

2,121,919

Deaths

160,172

330,091

38,672

157,566

10,442

385,521

183,735

Base case (realistic vaccination campaign**)

Costs saved

$ 266,754,782

$ 4,600,027,570

($ 3,167,869)

$ 942,846,561

$ 374,025,049

$ 9,689,633,010

$ 415,853,089

QALYs gained*

737,438

1,282,144

144,257

632,457

49,625

1,518,053

707,797

Deaths avoided

85,414

152,547

17,877

67,996

4,955

165,561

78,791

Cost-effectiveness

Cost-saving

Cost-saving

ICER: $22 per QALY gained

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Standard vaccination campaign***

Costs saved

$ 244,482,745

$ 4,650,194,020

$ 80,149,172

$ 1,220,452,465

$ 319,049,088

$ 9,291,807,794

$ 660,129,685

QALYs gained*

579,592

1,101,496

108,161

541,621

41,203

1,519,802

639,047

Deaths avoided

67,159

129,451

13,293

57,972

4,099

165,805

71,047

Cost-effectiveness

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Optimized vaccination campaign****

Costs Saved

$ 329,514,258

$ 4,488,290,446

$ 102,289,321

$ 1,358,560,340

$ 440,842,304

$ 11,123,858,434

$ 739,338,504

QALYs gained*

810,293

1,419,377

150,731

742,587

56,440

1,971,977

878,760

Deaths avoided

93,945

170,268

18,624

80,150

5,651

218,125

98,679

Cost-effectiveness

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Cost-saving

Cost-saving

  1. Base case (realistic vaccination campaign), standard and optimized scenarios
  2. *3% discount rate; **realistic vaccination campaign (weighted efficacy and costs by country-specific vaccine use, coverage, and costs); ***standard vaccination campaign: same vaccination campaign in all countries (weighted efficacy and costs); ****optimized but realistic campaign (see paper text for more details)
  3. Costs are expressed in American dollars for November 2021