Table 2 Study design and characteristics of positive effects on healthcare of DiGA listed in the DiGA directory (as of 02/28/2022).
From: Market access and value-based pricing of digital health applications in Germany
DiGA-Name | Indication(s) | Current listing statusa | Study designb | Patient-relevant improvements of structure and processes a | Medical benefita |
|---|---|---|---|---|---|
Kalmeda | Tinnitus | Final | RCT | – | tinnitus burden |
velibra | Generalized anxiety disorder, Panic disorder (with/without agoraphobia), Social phobias | Final | RCT | General mental stress | anxiety symptoms, depression symptoms |
somnio | Insomnia | Final | RCT | – | insomnia symptoms |
Vivira | Back pain | Final | RCT | – | back pain |
zanadio | Obesity | Provisional | RCT | – | body weight, body fat distribution, quality of life |
Invirto | Agoraphobia, panic disorder, social phobias | Provisional | RCT | – | anxiety symptoms, quality of life |
elevida | Fatigue in multiple sclerosis | Final | RCT | – | fatigue severity |
M-sense Migräne | Migraine | Provisional | RCT | Health literacy, Self–efficacy | migraine burden, quality of life |
Selfapys Online-Kurs bei Depression | Depression | Provisional | RCT | – | depression symptoms |
Rehappy | Stroke | Provisional | RCT | Adherence, Activities of daily living, Health literacy, Self–efficacy | relapse rate, depression symptoms, quality of life |
deprexis | Depression | Final | RCT | – | Depression symptoms |
Mika | Cancer | Provisional | RCT | – | Quality of life |
Mindable | Agoraphobia, panic disorder | Provisional | RCT | Health literacy, Anxiety–related control beliefs/ Self–efficacy, Activities of daily living | Anxiety symptoms, Panic symptoms, Quality of life |
CANKADO PRO-React Onco | Breast cancer | Provisional | n/a | Health literacy | – |
vorvida | Harmful alcohol consumption, Alcohol dependence | Final | RCT | Self–efficacy | Alcohol consumption |
Selfapys Online-Kurs bei Generalisierter Angststörung | Generalized anxiety disorder | Provisional | RCT | – | Anxiety symptoms, Depression symptoms |
Selfapys Online-Kurs bei Panikstörung | Panic disorder | Provisional | RCT | – | Anxiety symptoms, Depression symptoms |
NichtraucherHelden-App | Tobacco dependence | Provisional | RCT | – | Smoking prevalence, Quality of life |
ESYSTA App & Portal | Diabetes | Provisional | RCT | – | HbA1c |
Mawendo | knee pain | Provisional | RCT | – | Knee pain, Functional state |
Oviva Direkt für Adipositas | obesity | Provisional | RCT | – | Body weight |
companion patella | Knee pain | Provisional | RCT | – | Knee pain, Functional state |
Novego | Depression | Provisional | RCT | – | Depression symptoms |
HelloBetter Stress und Burnout | Stress, burnout | Final | RCT | – | Stress level |
HelloBetter Diabetes und Depression | Depression in diabetes mellitus | Final | RCT | – | Depression symptoms |
Kranus Edera | Impotence of organic origin | Provisional | RCT | Self–management | Erectile function, Quality of life |
HelloBetter ratiopharm chronischer Schmerz | Chronic pain | Provisional | RCT | – | Pain level |
Cara Care für Reizdarm | Irritable bowel syndrome | Provisional | RCT | Work productivity/ Activities of daily living, health literacy | Irritable bowel symptoms, Anxiety symptoms, Depression symptoms, Quality of life |
HelloBetter vaginismus plus | Vaginismus | Final | RCT | – | Vaginal penetration ability |
neolexon aphasie | Aphasia, apraxia | Provisional | RCT | – | Linguistic skills |