Table 1 MCDA EVIDEM Framework 10th Edition adapted to evaluation of interventions on thyroid nodules
Quantitative criteria: MCDA core model | Weighting example question | Scoring example question | |
|---|---|---|---|
Category | Criterion | How important do you consider the following criteria for decisions regarding healthcare interventions in general? (Weighting scale from 1 to 5, 5 is the highest relative importance) | Please evaluate the following criteria in connection with the current interventions on thyroid nodules (For non-comparative criteria from 0 to + 5, for comparative criteria from -5 to + 5, 5 is the highest score) |
Need for intervention | Disease severity | How important is disease severity for the need of interventions? | How severe is the disease as a thyroid nodule? |
Size of affected population | How important is the size of the population affected for the need of interventions? | How big is the affected population? | |
Unmet needs | How important is unmet need (that requirement cannot be met with current treatments) for the need of interventions? | Is there a large unmet need (i.e. need cannot be met with current treatments) for the interventions on thyroid nodules? | |
Comparative outcomes of intervention | Comparative efficacy/effectiveness | How important is effectiveness of the intervention? | How effective is the interventions on thyroid nodules? |
Comparative safety/tolerability | How important is safety of the intervention? | How safe is the interventions on thyroid nodules? | |
Comparative patient-perceived health | How important are patient-relevant endpoints after the intervention, e.g. health-related quality of life? | How should the interventions on thyroid nodules be assessed with regard to patient-relevant endpoints (e.g. quality of life)? | |
Type of benefit provided by intervention | Type of preventive benefit | How important are preventive benefits, e.g. reducing disease transmission? | How is the preventive benefit of the current interventions on thyroid nodules? |
Type of therapeutic benefit | How important are therapeutic benefits, e.g. healing, symptom relief? | How is the therapeutic benefit of the current interventions on thyroid nodules? | |
Comparative economic consequences of intervention | Comparative cost of intervention | How important are economic impacts as intervention costs to be considered? | How high are the costs of interventions on thyroid nodule? |
Comparative other medical costs | How important are economic impacts as other medical costs (for example, by through side effects, hospital stays) to be considered? | How high are the costs for other medical costs due to a thyroid nodule? | |
Comparative non-medical costs | How important are economic impacts as non-medical costs (for example, by disability, care) to be considered? | How high are the costs for non-medical costs due to a thyroid nodule? | |
Knowledge about the intervention | Quality of evidence | How important is the quality of scientific studies about the interventions? | How is the quality of scientific studies about the interventions on thyroid diseases? |
Clinical practice guidelines | How important is in-depth knowledge of expert opinions and guidelines about interventions? | How do you assess the interventions on thyroid nodules recommended in recognized guidelines? | |
Contextual Criteria: MCDA Contextual Tool | Please assess how the following criteria impact the current interventions on thyroid nodules (negative impact: -1, neutral impact: 0, positive impact: 1) | ||
Mandate and scope of the healthcare system | How are the healthcare system influence of the interventions on thyroid nodules? | ||
System capacity and appropriate use of intervention | How do you assess the system capacity and appropriate use of the interventions on thyroid nodules? | ||
Population priorities and access | How are population priorities and access to intervention influence of the interventions on thyroid nodules? | ||
Political/historical/cultural context | What are the effects of political, historical and / or cultural circumstances on the interventions on thyroid nodules? | ||