Fig. 1From: Cost-effectiveness evaluation of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine for children in TaiwanMarkov cohort model design. Rectangles represent mutually exclusive health states. Age-specific incidences are applied monthly to the susceptible population. Circles (sequelae and death) and small arrows (natural death) represent the proportion of the population removed from the model. Costs and benefits are computed monthly and aggregated over the cohort's lifetime. Non-consulting AOM episodes are accounted for in the quality-of-life calculation. Sp: Streptococcus pneumoniae; AOM: Acute Otitis Media; TTP: Tympanostomy Tube PlacementBack to article page