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Table 5 Assumptions and variations for sensitivities

From: Establishing a reasonable price for an orphan drug

Sensitivity − 20% Base case + 20%
Non-orphan population sizea 80 100 120
Competition in non-orphan marketsb 40% 50% 60%
Market exclusivity of orphans 8 years 10 years 12 years
  1. aValues standardised per 50,000 inhabitants
  2. bValues of market share
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