Table 2 Model inputs
Parameters | Base case value | Range tested (%) |
|---|---|---|
Unit drug costs (RMB) | ||
Unit cost of docetaxel (cost per mg) | 73.62 | ± 20 |
Unit cost of abiraterone (cost per mg) | 0.58 | ± 20 |
Unit cost of prednisolone/prednisone (cost per mg) | 1.33 | ± 20 |
Dosage | ||
Daily dosage of docetaxel (mg/m2) | 75 | ± 20 |
Daily dosage of abiraterone (mg) | 1000 | ± 20 |
Daily dosage of prednisolone (mg) | 5 | ± 20 |
Average height (m) | 1.615 | ± 20 |
Average weight (kg) | 61.8 | ± 20 |
Other medical costs (RMB) | ||
Hospitalisation costs for chemotherapy | 318 | ± 20 |
Preventive drugs for chemotherapy | 620 | ± 20 |
ADT cost per month | 2050 | ± 20 |
Laboratory test costs | 500 | ± 20 |
Inpatient OOP | 15 | ± 20 |
Outpatient OOP % | 25% | ± 20 |
Costs of adverse events (RMB) | ||
Hypertension | 98.70 | ± 50 |
Hypokalaemia | 65.00 | ± 50 |
ALT increased | 225.68 | ± 50 |
Hyperglycaemia | 115.00 | ± 50 |
AST increased | 225.68 | ± 50 |
Bone pain | 583.00 | ± 50 |
Cardiac disorder | 1000.00 | ± 50 |
Anaemia | 271.70 | ± 50 |
Back pain | 73.60 | ± 50 |
Spinal-cord compression | 1235.00 | ± 50 |
Fatigue | 540.44 | ± 50 |
Allergic reaction | 75.00 | ± 50 |
Diarrhoea | 31.44 | ± 50 |
Stomatitis | 74.00 | ± 50 |
Neuropathy | 375.84 | ± 50 |
Thromboembolism | 1794.20 | ± 50 |
Sudden death | 3200.00 | ± 50 |
Thrombocytopenia | 3518.04 | ± 50 |
Neutropaenia | 720.80 | ± 50 |
Febrile neutropaenia | 1787.20 | ± 50 |
Infection with neutropaenia | 14,764.05 | ± 50 |