Incorporating economies of scale in the cost estimation in economic evaluation of PCV and HPV vaccination programmes in the Philippines: a game changer?

Table 2 Cost of PCV vaccination (USD) for different percentages of vaccination coverage

% vaccine coverage	No. of vaccinated children	Average fixed cost	Average variable costs						Total cost of PCV vaccination per dose
		Cost of cold chain per vaccination	PCV10			PCV13			PCV10	PCV13
		Cost of cold chain per vaccination	Vaccine cost	Logistic and administration cost	Wastage cost	Vaccine cost	Logistic and administration cost	Wastage cost	PCV10	PCV13
10	220,000	1.20	14.74	2.95	0.74	16.54	3.31	0.83	19.63	21.87
20	440,000	0.60	14.25	2.85	0.71	15.86	3.17	0.79	18.41	20.42
30	660,000	0.40	13.76	2.75	0.69	15.18	3.04	0.76	17.60	19.37
40	880,000	0.30	13.26	2.65	0.66	14.49	2.90	0.72	16.88	18.42
50	1,100,000	0.24	12.77	2.55	0.64	13.81	2.76	0.69	16.20	17.50
60	1,320,000	0.20	12.28	2.46	0.61	13.13	2.63	0.66	15.54	16.61
70	1,540,000	0.17	11.78	2.36	0.59	12.45	2.49	0.62	14.90	15.73
80	1,760,000	0.15	11.29	2.26	0.56	11.76	2.35	0.59	14.26	14.86
90	1,980,000	0.13	10.79	2.16	0.54	11.08	2.22	0.55	13.63	13.99
100	2,200,000	0.12	10.30	2.06	0.52	10.40	2.08	0.52	12.99	13.12

Not taking into account economies of scale, the unit cost of PCV10 and PCV13 was USD 44.73 and USD 50.16
PCV pneumococcal conjugate vaccine

ISSN: 1478-7547