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Table 12 Incremental cost-effectiveness ratio of HPV vaccination alone compared to cervical cancer screening alone: Incremental cost-effectiveness ratio of HPV vaccination with applying economies of scale and cervical cancer screening without taking into account economies of scale

From: Incorporating economies of scale in the cost estimation in economic evaluation of PCV and HPV vaccination programmes in the Philippines: a game changer?

ICER (USD/QALY)

Percent coverage of screening (not taking into account EoS approach)

Percent coverage of HPV vaccine (with EoS approach)

% coverage

10

20

30

40

50

60

70

80

90

100

10

1860b

− 11100a

− 3480a

− 2540a

− 2140a

− 1890a

− 1720a

− 1580a

− 1450a

− 1340a

20

− 170a

700b

4160c

− 10880a

− 3830a

− 2680a

− 2170a

− 1860a

− 1640a

− 1470a

30

− 770a

− 540a

− 200a

470b

2770b

− 11610a

− 3190a

− 2130a

− 1670a

− 1380a

40

− 1190a

− 1120a

− 1060a

− 1000a

− 950a

− 920a

− 970a

− 4110a

− 160a

− 260a

50

− 1550a

− 1550a

− 1580a

− 1630a

− 1740a

− 1910a

− 2230a

− 2840a

− 4220a

− 9370a

60

− 1890a

− 1930a

− 2000a

− 2090a

− 2230a

− 2420a

− 2700a

− 3100a

− 3710a

− 4680a

70

− 2210a

− 2280a

− 2370a

− 2480a

− 2630a

− 2820a

− 3070a

− 3390a

− 3810a

− 4370a

80

− 2530a

− 2610a

− 2720a

− 2840a

− 2990a

− 3180a

− 3400a

− 3680a

− 4020a

− 4430a

90

− 2840a

− 2940a

− 3050a

− 3180a

− 3330a

− 3520a

− 3730a

− 3970a

− 4260a

− 4600a

100

− 3150a

− 3250a

− 3370a

− 3510a

− 3660a

− 3840a

− 4040a

− 4270a

− 4530a

− 4820a

  1. ICER incremental cost-effectiveness ratio, EoS economies of scale, HPV human papillomavirus vaccine
  2. aCost-effective
  3. bCost-ineffective
  4. cHighly cost-ineffective