Incorporating economies of scale in the cost estimation in economic evaluation of PCV and HPV vaccination programmes in the Philippines: a game changer?

Table 10 Incremental cost-effectiveness ratio of HPV vaccination alone compared to cervical cancer screening alone: Incremental cost-effectiveness ratio of HPV vaccination and cervical cancer screening without taking into account economies of scale

ICER (USD/QALY)	Percent coverage of screening (not taking into account EoS approach)
Percent coverage of HPV vaccine (not taking into account EoS approach)	% coverage	10	20	30	40	50	60	70	80	90	100
	10	1860^b	− 11100^a	− 3480^a	− 2540^a	− 2140^a	− 1890^a	− 1720^a	− 1580^a	− 1450^a	− 1340^a
	20	410^b	1670^b	6730^c	− 15430^a	− 5080^a	− 3420^a	− 2700^a	− 2280^a	− 1990^a	− 1770^a
	30	170^b	670^b	1510^b	3230^c	9470^c	− 30430^a	− 7260^a	− 4470^a	− 3330^a	− 2690^a
	40	60^b	370^b	780^b	1350^b	2250^b	3940^c	8580^c	114020^c	− 12250^a	− 6170^a
	50	10^b	230^b	490^b	810^b	1210^b	1750^b	2520^b	3800^c	6410^c	15380^c
	60	− 30^a	140^b	330^b	550^b	790^b	1080^b	1420^b	1850^b	2410^b	3200^c
	70	− 50^a	90^b	240^b	400^b	570^b	750^b	950^b	1180^b	1430^b	1720^b
	80	− 70^a	50^b	170^b	300^b	430^b	560^b	700^b	840^b	990^b	1140^b
	90	− 80^a	20^b	120^b	230^b	330^b	430^b	540^b	640^b	740^b	830^b
	100	− 90^a	0^b	90^b	170^b	260^b	340^b	430^b	500^b	570^b	640^b

ICER incremental cost-effectiveness ratio, EoS economies of scale, HPV human papillomavirus vaccine
^aCost-effective
^bCost-ineffective
^cHighly cost-ineffective

ISSN: 1478-7547