From: Cost-effectiveness of human papillomavirus vaccination in Germany
Parameter | Direct costs (€, 2010 price level) | |
---|---|---|
Vaccination costs | ||
 Vaccine (initial series of 3 doses) | 451.23 | |
 Administration (initial series of 3 doses) | 22.50 | |
 Booster shot (per dose) | 150.41 | |
 Administration of booster shot (per dose) | 7.50 | |
Costs of screening, management of abnormal cytological screening results, and observational follow-up of CIN 1 and CIN 2 | ||
 Cytological screening (Pap smear) | 25.23 | |
 Follow-up smear (including quarterly Gynaecologist’s fee and optional colposcopy) | ≤59 years | 20.15 |
60+Â years | 20.33 | |
 HPV test (including quarterly Gynaecologist’s fee) | ≤59 years | 44.77 |
60+Â years | 44.94 | |
 HPV test and follow-up smear (including quarterly Gynaecologist’s fee) | ≤59 years | 50.55 |
60+Â years | 50.73 | |
 Colposcopy (including quarterly Gynaecologist’s fee) | ≤59 years | 14.37 |
60+Â years | 14.54 | |
 Biopsy and histology | 129.47 | |
Costs of CIN/CIS treatment and post-treatment follow-up | ||
 Conisation of the cervix (CIN 1 and CIN 2) | ≤39 years | 525.05 |
40–59 years | 531.22 | |
60+Â years | 534.17 | |
 Treatment of CIN 3 and CIS | 1621.53 | |
 Post-treatment follow-up of CIN/CIS (year 1 and 2 after treatment) | ≤59 years | 70.71 |
60+Â years | 71.06 | |
Costs of cervical cancer treatment and post-treatment follow-up | ||
 Diagnostics of symptom-detected cervical cancer | ≤59 years | 323.03 |
60+Â years | 324.08 | |
 Diagnostics of screen-detected cervical cancer | ≤59 years | 179.18 |
60+Â years | 180.06 | |
 Treatment of cervical cancer (FIGO I) | ≤59 years | 7586.98 |
60+Â years | 7591.22 | |
 Treatment of cervical cancer (FIGO II) | ≤59 years | 11,455.22 |
60+Â years | 11,456.94 | |
 Treatment of cervical cancer (FIGO III) | ≤59 years | 12,380.21 |
60+Â years | 12,380.70 | |
 Treatment of cervical cancer (FIGO IV) | ≤59 years | 10,615.72 |
60+Â years | 10,616.21 | |
 Post-treatment follow-up of cervical cancer (year 1 after treatment) | ≤49 years | 841.53 |
50–59 years | 835.65 | |
60+Â years | 836.35 | |
 Post-treatment follow-up of cervical cancer (year 2 after treatment) | ≤49 years | 428.13 |
50–59 years | 422.25 | |
60+Â years | 422.95 | |
 Post-treatment follow-up of cervical cancer (year 3 after treatment) | ≤49 years | 352.42 |
50–59 years | 346.54 | |
60+Â years | 347.24 | |
 Post-treatment follow-up of cervical cancer (year 4 and 5 after treatment) | ≤49 years | 282.50 |
50–59 years | 276.62 | |
60+Â years | 276.97 | |
 Post-treatment follow-up of cervical cancer (from year 6 after treatment onwards) | ≤49 years | 262.35 |
50–59 years | 256.47 | |
60+Â years | 256.65 | |
 Inpatient palliative care and treatment | 7518.09 | |
Costs of genital warts treatment | ||
 Treatment of genital warts in females | 572.14 | |
 Treatment of genital warts in males | 396.69 |