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Table 3 Direct health care costs

From: Cost-effectiveness of human papillomavirus vaccination in Germany

Parameter

Direct costs (€, 2010 price level)

Vaccination costs

 Vaccine (initial series of 3 doses)

451.23

 Administration (initial series of 3 doses)

22.50

 Booster shot (per dose)

150.41

 Administration of booster shot (per dose)

7.50

Costs of screening, management of abnormal cytological screening results, and observational follow-up of CIN 1 and CIN 2

 Cytological screening (Pap smear)

25.23

 Follow-up smear (including quarterly Gynaecologist’s fee and optional colposcopy)

≤59 years

20.15

60+ years

20.33

 HPV test (including quarterly Gynaecologist’s fee)

≤59 years

44.77

60+ years

44.94

 HPV test and follow-up smear (including quarterly Gynaecologist’s fee)

≤59 years

50.55

60+ years

50.73

 Colposcopy (including quarterly Gynaecologist’s fee)

≤59 years

14.37

60+ years

14.54

 Biopsy and histology

129.47

Costs of CIN/CIS treatment and post-treatment follow-up

 Conisation of the cervix (CIN 1 and CIN 2)

≤39 years

525.05

40–59 years

531.22

60+ years

534.17

 Treatment of CIN 3 and CIS

1621.53

 Post-treatment follow-up of CIN/CIS (year 1 and 2 after treatment)

≤59 years

70.71

60+ years

71.06

Costs of cervical cancer treatment and post-treatment follow-up

 Diagnostics of symptom-detected cervical cancer

≤59 years

323.03

60+ years

324.08

 Diagnostics of screen-detected cervical cancer

≤59 years

179.18

60+ years

180.06

 Treatment of cervical cancer (FIGO I)

≤59 years

7586.98

60+ years

7591.22

 Treatment of cervical cancer (FIGO II)

≤59 years

11,455.22

60+ years

11,456.94

 Treatment of cervical cancer (FIGO III)

≤59 years

12,380.21

60+ years

12,380.70

 Treatment of cervical cancer (FIGO IV)

≤59 years

10,615.72

60+ years

10,616.21

 Post-treatment follow-up of cervical cancer (year 1 after treatment)

≤49 years

841.53

50–59 years

835.65

60+ years

836.35

 Post-treatment follow-up of cervical cancer (year 2 after treatment)

≤49 years

428.13

50–59 years

422.25

60+ years

422.95

 Post-treatment follow-up of cervical cancer (year 3 after treatment)

≤49 years

352.42

50–59 years

346.54

60+ years

347.24

 Post-treatment follow-up of cervical cancer (year 4 and 5 after treatment)

≤49 years

282.50

50–59 years

276.62

60+ years

276.97

 Post-treatment follow-up of cervical cancer (from year 6 after treatment onwards)

≤49 years

262.35

50–59 years

256.47

60+ years

256.65

 Inpatient palliative care and treatment

7518.09

Costs of genital warts treatment

 Treatment of genital warts in females

572.14

 Treatment of genital warts in males

396.69

  1. CIN cervical intraepithelial neoplasia, CIS carcinoma in situ, FIGO International Federation of Gynecology and Obstetrics