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Table 3 Disease events prevented with the nine-valent vaccine universal vaccination in comparison with the current strategy (the quadrivalent vaccine girls-only vaccination)

From: Cost-effectiveness analysis of the nine-valent HPV vaccine in Italy

Disease event

Years since start of vaccination programme

5

25

50

100

Females

 Cervical cancer

0

367

4623

22,640

 CIN 1

23

6961

34,753

105,431

 CIN 2/3

25

10,193

54,709

170,286

 Vaginal cancer

0

0

13

88

 VAIN 2/3

0

0

0

0

 Vulvar cancer

0

1

21

130

 Genital warts and HPV 6/11-related CIN 1

33

2438

6270

13,658

 Genital warts

1411

61,285

161,443

358,140

 Anal cancer

0

11

318

2619

Males

 Genital warts

6101

208,935

615,645

1508,705

 Anal cancer

0

28

748

5492