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Table 2 Background epidemiological and program data

From: Optimizing treatment for the prevention of pre-eclampsia/eclampsia in Nepal: is calcium supplementation during pregnancy cost-effective?

Parameter Base case Low High Distribution for PSA
Maternal careseeking
 ANC, at least one visit 84.8% [35] 63.60% 100% Beta
 Facility deliveries in government sector 26.0% [35] 19.5% 32.5% Beta
Screening procedures
 Blood pressure 86.4% [35] 64.80% 100% Beta
 Urine sample 55.9% [35] 41.9% 69.9% Beta
 Blood sample 45.3% [35] 34.0% 56.63% Beta
Eclampsia epidemiology
 Incidence of eclampsia 4.30% [9] 3.23% 5.38% Beta
 Eclampsia as direct maternal cause of death 21.0% [10] 15.8% 26.3% Beta
 Mean age of eclampsia patients 23.4 [38] 17.7 [38] 29.2 [38]
Treatment
 MgSO4 for PE/E management 68.9%a 51.7% 95.8% Beta
 Cesarean delivery 55.31% [46] 41.5% 69.1% Beta
Maternal risk ratios for PE/E
 Calcium supplementation 0.45 [15] 0.31 [15] 0.65 [15] Beta
 MgSO4, standard regimen 0.19 [19] 0.14 [19] 0.24 [19] Beta
 Cesarean delivery 0.55 [25] 0.41 [25] 0.69 [25] Beta
Still birth rates
 Vaginal birth 1.37%a 1.03% 1.71% Beta
 Cesarean delivery 0.43%a 0.32% 0.54% Beta
 Vaginal birth among PE/E cases 14.3%a 10.7% 17.9% Beta
 Cesarean delivery among PE/E cases 9.77%a 7.33% 12.2% Beta
Disability-adjusted life years (DALYs)
 DALYs averted per individual (maternal) 24.9b 15.6c 31.8d
 DALYs averted per individual (newborn) 29.0b 16.4c 32.3d
Pilot Program Data, Dailekh District, 2013
 Maternal careseeking
  ANC, at least one visit 94.6% 71.0% 100% Beta
 Calcium regimen compliance
  Full compliance 67.3% 50.5% 84.1%
  Partial or low compliance 32.7% 24.5% 40.9%
 Gestational age among women receiving calcium
  4–5 months (300 calcium tablets) 82.2% 61.7% 95%
  6–7 months (200 calcium tablets) 13.8% 25.6% 2.5%
  8–9 months (100 calcium tablets) 4.0% 12.8% 2.5%
 Screening procedures
  Blood pressure 98% 73.5% 100% Beta
  Urine test 97% 72.8% 100% Beta
  1. aSource: Jhpiego/MCHIP
  2. bDiscount rate 3% + no age weighting
  3. cDiscount rate 6% + age weighting
  4. dDiscount rate 3% + age weighting