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Table 5 One way sensitivity analyses results

From: Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation

 

Kenya

Tanzania

Botswana

South Africa

Probability of requiring a transfusion without TXA

    

0%

$13,000a

$13,000a

$13,000a

$13,000a

100%

$58b

$63b

-$97,000a

-$97,000a

Probability of death for a patient not receiving transfusion

    

75%

$380b

$416b

-$59,000a

-$59,000a

15%

$50b

$53b

-$59,000a

-$59,000a

Cost of TXA

    

$3.13

$54b

$59b

-$64,000a

-$64,000a

$44

$327b

$350b

-$23,000a

-$23,000a

Cost of one unit of blood

    

$15.6

$87b

$93b

-$6,000a

-$6,000a

$262

$87b

$93b

-$316,000a

-$316,000a

Probability of death for a surgery patient in SSA

    

11%

$100b

$108b

-$59,000a

-$59,000a

4%

$83b

$88b

-$59,000a

-$59,000a

RR of requiring transfusion with TXA vs. no TXA

    

0.54

$78b

$88b

-$64,000a

-$64,000a

0.69

$102b

$172b

-$52,000a

-$52,000a

Number of units transfused without TXA

    

2.52

$105b

$110b

$-36,000a

$-36,000a

3.73

$74b

$81b

$-81,000a

$-81,000a

  1. a rounded to the nearest thousand
  2. b Incremental cost per life saved