Cost-effectiveness model comparing olanzapine and other oral atypical antipsychotics in the treatment of schizophrenia in the United States

Table 7 Economic Input Parameters

A: Medication Costs
	Cost		Mean Modal Daily Dose (mg)
Olanzapine	$15.44		15			NWP Prices, Analysource Data, January 30, 2007 [79]
Risperidone-generic	$5.00		4			Doses: Conley and Mahmoud, 2001 [77];
Quetiapine	$14.79		500			Tunis et al., 2006 [49];
Ziprasidone	$9.81		100			Lieberman et al., 2005 [23]; Kern et al., 2006 [78];
Aripiprazole	$10.92		15			Generic risperidone NWP price = $5.00 per 4 mg/day
B: Health Service Resource Utilization
Health Service	Per Stable Quarter*	Per Outpatient Relapse Event*	Per Inpatient Relapse Event*	Extrapyramidal Symptoms (EPS)*	Clinically Significant Weight Gain*
Hospitalization days	0.0	0.0	11.7**	0.0	0.0
Day hospital treatment, day	0.0	1.25	1.25	0.0	0.0
Emergency room visits	0.0	1.0	1.0	0.0	0.0
Physician visits	3.0	1.0	1.0	1.0	0.5	*Edwards et al., 2005 [18];
Mental health clinic visits	4.5	2.0	2.0	1.0	2.5	**AHRQ HCUP [82]
Home care hour	0.0	2.75	2.75	0.0	0.0
Group intervention hour	1.5	1.5	1.5	0.0	5.0
Nutritionist visits	0.0	0.0	0.0	0.0	2.5
C: Unit Costs of Health Service Resources
Inpatient hospital, per day	$828					AHRQ HUCP [82]
Day hospital treatment, per day	$501					Edwards et al., 2005 [18]
Emergency room visit	$480
Outpatient Care
Physician visit	$74
Mental health clinic visit	$75
Home health care (per hour)	$82
Group therapy (per hour)	$71
Nutritionist visit (per hour)	$111

ISSN: 1478-7547