Cost-effectiveness of tipranavir versus comparator protease inhibitor regimens in HIV infected patients previously exposed to antiretroviral therapy in the Netherlands

Table 1 Health states with associated risks of AIDS events and quality of life weights

Heath State	CD4+ count¹	Viral load²	AIDS events³ [18]	Quality of Life weight [19]
1	>500	Undetectable	1.71	0.954
2	>500	Detectable	2.18	0.938
3	351–500	Undetectable	1.71	0.934
4	351–500	Detectable	2.18	0.931
5	201–350	Undetectable	2.84	0.929
6	201–350	<10,000	3.31	0.931
7	201–350	=>10,000	4.25	0.933
8	50–200	Undetectable	5.11	0.863
9	50–200	<10,000	5.58	0.865
10	50–200	10,000–100,000	9.79	0.826
11	50–200	>100,000	14.47	0.876
12	<50	Any viral load	17.87	0.781

The 12 health states defined by CD4+ counts and viral load. Also shown are the associated risks of AIDS events and quality of life (QOL) weights for each health state.
¹ Number of CD4+ cells per micro liter
² RNA copies/mL (as measured by the Roche Amplicor HIV-1 Monitor)
³ Number of events per 100 patients over a 3-month period

ISSN: 1478-7547