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Table 5 Sensitivity analysis of DEX, BORT and LEN/DEX: costs and cost-effectiveness ratios

From: Cost utility and budget impact analysis of dexamethasone compared with bortezomib and lenalidomide for the treatment of second line multiple myeloma from a South African public health perspective

Sensitivity

Treatment

Cost (R)

ICER (cost/QALY)

Discount rate 0%

DEX

R 9001

 

BORT

R 257 906

605 569

LEN/DEX

R 1 312 357

1 147 418

Discount rate 10%

DEX

R 7 741

 

BORT

R 216 818

702 510

LEN/DEX

R 1 003 823

1 299 670

Outpatient costs − 50%

DEX

R 4 960

 

BORT

R 215 460

607 912

LEN/DEX

R 1 130 014

1 244 907

Outpatient costs + 50%

DEX

R 11 664

 

BORT

R 254 531

701 385

LEN/DEX

R 1 140 632

1 206 177

Inpatient costs − 50%

DEX

R 7 598

 

BORT

R 234 393

654 972

LEN/DEX

R 1 134 750

1 225 582

Inpatient costs + 50%

DEX

R 9 027

 

BORT

R 235 598

654 325

LEN/DEX

R 1 135 897

1 225 502

LEN drug price − 40%

DEX

R 8  312

 

BORT

R 234 996

Dominated

LEN/DEX

R 386 478

349 861

LEN drug price + 40%

DEX

R 8 312

 

BORT

R 234 996

654 649

LEN/DEX

R 1 884 168

2 244 883

BORT drug price − 40%

DEX

R 8 312

 

BORT

R 96 891

279 817

LEN/DEX

R 1 030 119

1 402 216

BORT drug price + 40%

DEX

R 8 312

 

BORT

R 589 737

Dominated

LEN/DEX

R 1 135 323

742 662