Table 1 Model input parameters
Input | Base case estimate | Source |
|---|---|---|
Utilisation rates per 4-week cycle | ||
 Inpatient days DEX | 0.02 | [27] |
 Inpatient days BORT | 0.0158 | [27] |
 Inpatient days LEN/DEX | 0.0125 | [27] |
 Outpatient visits DEX | 0.3875 | [27] |
 Outpatient visits BORT | 0.5025 | [27] |
 Outpatient visits LEN/DEX | 0.3325 | [27] |
 DEX units used | 480 mg (first 4 cycles) 160 mg (cycle 5 onward) | [28] |
 BORT units used | 13.5 mg (first 8 cycles) 9 mg (cycle 9 onward) | [28] |
 LEN/DEX unit used | 525 mg | [28] |
Unit costs | ||
 Cost per inpatient day | R 4 515.80 | [29] |
 Cost per outpatient visit (NIC) | R 800.00 | [26] |
 Cost per outpatient visit (IC) | R 2 837.00 | [26] |
 Cost of DEX 40 mg | R 6.28 | [25] |
 Cost of LEN 25 mg | R 1 340.03 | [16] |
 Cost of BORT 1 mg/ml | R 865.47 | [16] |