Table 2 Quality of Health Economic Studies (QHES)
Castro-Jaramillo (2012) | Kanters et al. (2014) | Kanters et al. (2017) | Rombach S.M. et.al., (2013) | Van Dussen L. et.al., (2014) | NCPE | |
|---|---|---|---|---|---|---|
Was the study objective presented in a clear, specific, and measurable manner? | 7 | 7 | 7 | 7 | 7 | 7 |
Were the perspective of the analysis (societal, third-party payer, etc.) and reason for its selection stated | 4 | 4 | 4 | 4 | 4 | |
Were variable estimates used in the analysis from the best available source (i.e. Randomized Control Trial –Best, Expert Opinion –Worst)? | 8 | 8 | 8 | 8 | 8 | 8 |
If estimates came from a subgroup analysis, were the groups prespecified at the beginning of the study? | 1 | 1 | 1 | 1 | 1 | 1 |
5) Was uncertainty handled by: 1) statistical analysis to address random events; 2) sensitivity analysis to cover a range of assumptions? | 9 | 9 | 9 | 9 | 9 | 9 |
Was incremental analysis performed between alternatives for resources and costs? | 6 | 6 | 6 | 6 | 6 | 6 |
Was the methodology for data abstraction (including the value of health states and other benefits) stated? | 5 | 5 | 5 | 5 | ||
Did the analytic horizon allow time for all relevant and important outcomes? Were benefits and cost that went beyond one year discounted and a justification given for the discount rate? | 7 | 7 | 7 | 7 | 7 | 7 |
Was the measurement of costs appropriate and the methodology for the estimation of quantities and unit costs clearly described? | 8 | 8 | 8 | 8 | 8 | |
Were the primary outcome measure(s) for the economic evaluation clearly stated and were the major short-term, long-term, and negative outcomes included? | 6 | 6 | 6 | 6 | 6 | 6 |
Were the health outcomes measures/scales valid and reliable? If previously tested, valid and reliable measures were not available, was justification given for the measures/scale and reliable measures were not available, was justification given for the measures/scale used? | 7 | 7 | 7 | 7 | 7 | 7 |
Was the economic model (including structure), study methods and analysis, and the components of the numerator and denominator displayed in a clear transparent manner? | 8 | 8 | 8 | 8 | 8 | |
Were the choice of economic model, main assumptions and limitations of the study stated and justified? | 7 | 7 | 7 | 7 | 7 | |
Did the author(s) explicitly discuss direction and magnitude of potential biases? | 6 | |||||
Were the conclusion/ recommendations of the study justified and based on the study results? | 8 | 8 | 8 | 8 | 8 | 8 |
Was there a statement disclosing the source of funding for the study? | 3 | 3 | 3 | |||
Total score | 91 | 91 | 81 | 94 | 100 | 67 |