Table 3 Model outcomes including infections averted, incremental costs, incremental QALYs, and incremental cost-effectiveness ratio for upgrading the room ventilation rate from 0.8 to 12 ACH
| Â | Airborne infections averted Mean (95% credible interval) | Net cost ($) Mean (95% credible interval) | Cost saving ($) Mean (95% credible interval) | Losses of QALYs Mean (95% credible interval) | Incremental QALYsa gained Mean (95% credible interval) | ICERb (95% credible interval) |
|---|---|---|---|---|---|---|
Base-case scenario (2% prevalence of disease in the surrounding community where the restaurant is located and when 70% of the customers are vaccinated) | ||||||
 Room ventilation rate of 0.8 ACH |  | $185,579 ($100,099, $300,430) |  | 1.6 (0.85, 2.66) |  |  |
 Improve room ventilation rate to 12 ACH | 54 (29, 86) | $32,877 ($19,394, $50,877) | $152,701 ($80,663, $249,501) | 0.25 (0.13, 0.42) | 1.35 (0.72, 2.24) | − $113,126/QALY (dominant, dominant) |
Best-case scenario (0.1% prevalence of disease in the surrounding community where the restaurant is located and when 90% of the restaurant customers are vaccinated) | ||||||
 Room ventilation rate of 0.8 ACH |  | $6824 ($3524, $11,356) |  | 0.06 (0.03, 0.11) |  |  |
 Improve room ventilation rate to 12 ACH | 2 (1, 4) | $4821 ($3930, $5865) | $2003 (− $881, $5968) | 0.01 (0.01, 0.02) | 0.05 (0.03, 0.09) | − $38,104/QALY (dominant, $30,503/QALY) |
Worst-case scenario (3% prevalence of disease in the surrounding community where the restaurant is located and when no customer is vaccinated) | ||||||
 Room ventilation rate of 0.8 ACHc |  | $544,521 ($298,694, $875,492) |  | 4.35 (2.34, 7.14) |  |  |
 Improve room ventilation rate to 12 ACH | 135 (76, 213) | $89,243 ($50,540, $141,203) | $455,277 ($247,879, $734,424) | 0.68 (0.37, 1.12) | 3.66 (1.98, 6.02) | − $124,294/QALY (dominant, dominant) |