Table 3 Results of the models
| Â | Time point | RMM | RMFE | CCA | MIPMM | MILR | BPA |
|---|---|---|---|---|---|---|---|
Differences in mean costs (standard error) (95% confidence interval) (£) | 1-year | N = 450 − 70 (482) CI (− 1014 to 874) | N = 450 − 93 (525) CI (− 1123 to 936) | N = 338 − 4 (326) CI (− 644 to 636) | N = 450 50 (295) CI (− 528 to 627) | N = 450 (307) CI (− 534 to 669) | N = 450 137(305) CI (− 340 to 665) |
3-years | N = 450 − 159 (565) CI (− 1265 to 949) | N = 450 − 180 (610) CI (− 1375 to 1015) | N = 44 215 (831) CI (− 1531 to 148) | N = 450 25 (312) CI (− 586 to 637) | N = 450 58 (328) CI (− 583 to 700) | N = 450 − 38 (360) CI (− 637 to 556) | |
5-years | N = 450 − 93 (651) CI (− 1369 to 1184) | N = 450 − 111 (697) CI (− 1477 to 1255) | N = 147 464 (751) CI (− 1008 to 1936) | N = 450 8 (333) CI (− 645 to 661) | N = 450 57 (354) CI (− 637 to 751) | N = 450 1200 (807) CI (− 122 to 2536) | |
Differences mean QALY (standard error) (95% confidence interval) | 1-year | N = 450 0.05 (0.02) CI (0.02 to 0.08) | N = 450 0.05 (0.02) CI (0.02 to 0.08) | N = 338 0.04 (0.02) CI (0.01 to 0.07) | N = 450 0.05 (0.02) CI (0.01 to 0.08) | N = 450 0.05 (0.02) CI (0.01 to 0.08) | N = 450 0.05(0.02) CI (0.02 to 0.78) |
3-years | N = 450 0.07 (0.07) CI (− 0.06 to 0.20) | N = 450 0.07 (− 0.07) CI (− 0.06 to 0.20) | N = 44 0.04 (0.13) CI (− 0.21 to 0.29) | N = 450 0.08 (0.05) CI (− 0.04 to 0.20) | N = 450 0.09 (0.08) CI (− 0.07 to 0.25) | N = 450 0.12 (0.13) CI (0.09 to 0.34) | |
5-year | N = 450 0.05 (0.11) CI (− 0.16 to 0.26) | N = 450 0.05 (0.11) CI (− 0.16 to 0.26) | N = 147 0.01 (0.12) CI (− 0.24 to 0.25) | N = 450 0.05 (0.08) CI (− 0.10 to 0.20) | N = 450 05 (0.12) CI (− 0.20 to 0.31) | N = 450 0.16 (0.17) CI (− 0.03 to 0.58) | |
ICER £/QALY | 1-year | Dominant | Dominant | Dominant | 1082 | 1430 | 2728 |
3-years | Dominant | Dominant | 6075 | 319 | 627 | Dominant | |
5-years | Dominant | Dominant | 59,500 | 159 | 1010 | 7394 |