Table 1 Costs and model values

Mortality

 Age < 14 years

0.11

0.11

[26]

 Severe malaria

0.23

0.36

[31]

Transition probabilities

 Healthy-death

0.11

[26]

 Disease-death

0.23

[31]

 Healthy-disease

0.03

[13]

 Hospitalization

0.98

[13]

Drug costs

 Artesunate drug

7.8

 Other drugs

3.6

 Fluids

10.7

 Laboratory tests

6.4

 Nursing care

37.1

 Total drug cost

65.6

66

9

30,625

0.0000229

Gamma

[24, 32,33,34]

 Quinine drug

2.6

[24, 32, 35]

 Other drugs

3.8

 Fluids

11.0

 Laboratory tests

6.6

 Nursing care

37.4

 Total drug cost

61.4

61

6

225,000

0.0001333

Gamma

 Cost hospitalization

65

65

19

11.7036011

6

Gamma

[24, 36, 37]

Hazard ratio

 HR die artesunate

0.78

64

0.01

–

–

Normal

[22, 38]

 HR disease artesunate

0.64

64

0.01

-

–

Normal

[22, 38]

 HR hospitalization artesunate

1.02

1

0.001

–

–

Normal

[22, 38, 39]

Utility

 Utility healthy

0.98

0.98

0.07

3

0

Beta

[12, 40, 41]

 Utility disease

0.80

0.80

0.05

50

13

Beta

[12, 42, 43]

 Utility decrement hospitalization

0.1

0.1

0.08

1

12

Beta

[13, 43]

 Discount rate

5.0%

5.0%

–

–

–

–

–

[1]