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Table 3 Base case results of sitagliptin versus without sitagliptin (in Egyptian Pounds)

From: A budget impact analysis of substituting sitagliptin with liraglutide in type 2 diabetes from a private health insurance perspective in Egypt

Parameter

Year 1

Year 2

Year 3

Cumulative

Cost of sitagliptin acquisition

14,324,166

3,331,201 USD

19,098,888

4,441,601 USD

23,873,610

5,552,002 USD

57,296,665

13,324,805 USD

Cost of standard of care by substitutiona

(5,823,714)

1,354,352 USD

(7,764,952)

1,805,802 USD

(9,706,190)

2,257,253 USD

(23,294,856)

5,417,408 USD

Drug cost

8,500,452

1,976,849 USD

11,333,936

2,635,799 USD

14,167,420

3,294,748 USD

34,001,809

7,907,397 USD

MI

(277,509)

64,536 USD

(370,012)

86,049 USD

(462,515)

107,561 USD

(1,110,037)

258,148 USD

Ischemic stroke

(476,953)

110,919 USD

(635,938)

151,413 USD

(794,922)

184,865

USD

(1,907,813)

443,677 USD

Hospitalization for unstable angina

(555,019)

129,074 USD

(740,025)

172,098 USD

(925,031)

215,123 USD

(2,220,074)

516,296 USD

Severe hypoglycemia

87,453

20,337 USD

116,605

27,117 USD

145,756

33,896 USD

349,814

81,352 USD

CV death

8,138,731

1,892,728 USD

10,851,641

2,523,637 USD

13,564,551

3,154,546 USD

32,554,923

7,570,912 USD

Hospitalization for heart failure or CV death

583,273

135,644 USD

777,697

180,859 USD

972,121

226,074 USD

2,333,091

542,579 USD

Acute pancreatitis

202,139

47,009 USD

269,519

62,678 USD

336,898

78,348 USD

808,556

188,036 USD

Pancreatic cancer

(333,276)

77,506 USD

(444,367)

103,341 USD

(555,459)

129,176 USD

(1,333,102)

310,023 USD

Medical costs

7,368,839

1,713,683 USD

9,825,119

2,284,911 USD

12,281,399

2,856,139 USD

29,475,358

6,854,734 USD

Total costs PPPM

11

2.55 USD

14

3.25 USD

18

4.18 USD

14

3.25 USD

  1. PPPM per patient per month
  2. aWe substituted the market share of the glucose lowering drugs with sitagliptin