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Table 3 Comparison of mortality risks between patients admitted for different stroke type with different comorbidity categories

From: Temporal trend of comorbidity and increasing impacts on mortality, length of stay, and hospital costs of first stroke in Tianjin, North of China

Comorbidity burdena

In-hospital Mortality

7-day Mortality

Univariable Analysis

Multivariable Analysis

Univariable Analysis

Multivariable Analysis

HR (95% CI)

P value

aHR (95% CI)

P value

HR (95% CI)

P value

aHR (95% CI)

P value

Ischemic stroke

 None

1.00

   

1.00

 

1.00

 

 Moderate

1.62 (1.14–2.30)

0.007

1.57 (1.11–2.23)

0.012

1.34 (0.84–2.13)

0.215

1.27 (0.80–2.02)

0.310

 Severe

3.38 (2.27–5.04)

< 0.001

2.68 (1.79–4.00)

< 0.001

3.51 (2.10–5.87)

< 0.001

3.32 (2.02–5.45)

< 0.001

 Very severe

3.95 (2.71–5.75)

< 0.001

3.86 (2.65–5.61)

< 0.001

3.59 (2.18–5.89)

< 0.001

3.32 (2.02–5.45)

< 0.001

Hemorrhagic stroke

 None

1

 

1

 

1.00

 

1.00

 

 Moderate

0.98 (0.26–3.70)

0.975

0.92 (0.24–3.49)

0.904

0.88 (0.18–4.38)

0.880

0.80 (0.16–4.00)

0.790

 Severe

3.91 (1.45–10.56)

0.007

3.97 (1.47–10.70)

0.006

3.49 (1.07–11.44)

0.039

3.51 (1.07–11.52)

0.038

 Very severe

3.88 (1.40–10.76)

0.009

3.95 (1.42–10.99)

0.008

4.78 (1.54–14.84)

0.007

4.88 (1.57–15.14)

0.006

  1. aHR adjusted hazard ratio, HR hazard ratio
  2. aFour categories of comorbidity were defined based on Charlson Comorbidity Index scores of 0 (none), 1 (moderate), 2 (severe), and 3 or more (very severe)