Variables | Total (n = 5988) | Comorbidity category | P value | |||
---|---|---|---|---|---|---|
None (n = 2878) | Moderate (n = 1972) | Severe (n = 545) | Very severe (n = 593) | |||
Age (mean ± SD) | 69.3 ± 12.4 | 68.3 ± 12.7 | 69.6 ± 12.1 | 73.5 ± 11.2 | 70.2 ± 12.3 | < 0.001 |
Sex, N (%) | ||||||
 Female | 2493 (41.6) | 1096 (38.1) | 892 (45.2) | 254 (46.6) | 251 (42.3) |  |
Age group, N (%) | < 0.001 | |||||
 18–34 years | 23 (0.4) | 12 (0.4) | 5 (0.3) | 2 (0.4) | 4 (0.7) |  |
 35–44 years | 121 (2.0) | 74 (2.6) | 31 (1.6) | 7 (1.3) | 9 (1.5) |  |
 45–54 years | 627 (10.5) | 339 (11.8) | 213 (10.8) | 23 (4.2) | 52 (8.3) |  |
 55–64 years | 1412 (23.6) | 757 (26.3) | 444 (22.5) | 83 (15.2) | 128 (21.6) |  |
 65–74 years | 1431 (23.9) | 645 (22.4) | 499 (25.3) | 142 (26.1) | 145 (24.5) |  |
 75–84 years | 1757 (29.3) | 776 (27.0) | 589 (29.9) | 202 (37.1) | 190 (32.0) |  |
 ≥ 85 years | 617 (10.3) | 275 (9.6) | 191 (9.7) | 86 (15.8) | 65 (11.0) |  |
Comorbidities, N (%) | ||||||
 Hypertension | 4758 (79.5) | 2264 (78.7) | 1578 (80.0) | 429 (78.7) | 487 (82.1) | 0.235 |
 Atrial fibrillation or flutter | 858 (14.3) | 353 (12.3) | 285 (14.5) | 118 (21.7) | 102 (17.2) | < 0.001 |
 Myocardial infarction | 365 (6.1) | 0 (0) | 132 (6.7) | 153 (28.1) | 80 (13.5) | < 0.001 |
 Congestive heart failure | 524 (8.8) | 0 (0) | 185 (9.4) | 157 (28.8) | 182 (30.7) | < 0.001 |
 Peripheral vascular disease | 256 (4.3) | 0 (0) | 76 (3.9) | 68 (12.5) | 112 (18.9) | < 0.001 |
 Dementia | 86 (1.4) | 0 (0) | 52 (2.6) | 27 (5.0) | 7 (1.2) | < 0.001 |
 Chronic pulmonary disease | 48 (0.8) | 0 (0) | 20 (1.0) | 17 (3.1) | 11 (1.9) | < 0.001 |
 Connective tissue disease | 93 (1.6) | 0 (0) | 52 (2.6) | 23 (4.2) | 18 (3.0) | < 0.001 |
 Ulcer disease | 106 (1.8) | 0 (0) | 46 (2.3) | 33 (6.1) | 27 (4.6) | < 0.001 |
 Mild liver disease | 59 (1.0) | 0 (0) | 22 (1.1) | 20 (3.7) | 17 (2.9) | < 0.001 |
 Diabetes without end-organ damage | 2084 (34.8) | 0 (0) | 1387 (70.3) | 268 (49.2) | 429 (72.3) | < 0.001 |
 Diabetes with end-organ damage | 223 (3.7) | 0 (0) | 0 (0) | 0 (0) | 223 (37.6) | < 0.001 |
 Moderate to severe renal disease | 228 (3.8) | 0 (0) | 0 (0) | 71 (13.0) | 157 (26.5) | < 0.001 |
 Nonmetastatic solid tumor | 201 (3.4) | 0 (0) | 0 (0) | 88 (16.1) | 113 (19.1) | < 0.001 |
 Leukemia | 7 (0.1) | 0 (0) | 0 (0) | 2 (0.4) | 5 (0.8) | < 0.001 |
 Lymphoma | 3 (0.1) | 0 (0) | 0 (0) | 1 (0.2) | 2 (0.3) | 0.003 |
 Moderate to severe liver disease | 74 (1.2) | 0 (0) | 0 (0) | 0 (0) | 74 (12.5) | < 0.001 |
 Metastatic cancer | 16 (0.3) | 0 (0) | 0 (0) | 0 (0) | 16 (2.7) | < 0.001 |
Stroke type, N (%) | < 0.001 | |||||
 Ischemic stroke | 5751 (96.0) | 2749 (95.5) | 1924 (97.6) | 513 (94.1) | 565 (95.3) |  |
 Hemorrhagic stroke | 237 (4.0) | 129 (4.5) | 48 (2.4) | 32 (5.9) | 28 (4.7) |  |
Season, N (%) | 0.263 | |||||
 Spring | 1481 (24.7) | 707 (24.6) | 518 (26.3) | 133 (24.4) | 123 (20.7) |  |
 Summer | 1519 (25.4) | 756 (26.3) | 475 (24.1) | 136 (25.0) | 152 (25.6) |  |
 Fall | 1484 (24.8) | 716 (24.9) | 480 (24.3) | 136 (25.0) | 152 (25.6) |  |
 Winter | 1504 (25.1) | 699 (24.3) | 499 (25.3) | 140 (25.7) | 166 (28.0) |  |
Week, N (%) | 0.464 | |||||
 Weekend | 1625 (27.1) | 796 (27.7) | 510 (25.9) | 155 (28.4) | 164 (27.1) |  |
 Weekday | 4363 (72.9) | 2082 (72.3) | 1462 (74.1) | 390 (71.6) | 429 (72.3) |  |
Payer, N (%) | < 0.001 | |||||
 Urban employee basic medical insurance | 4540 (75.8) | 2139 (74.3) | 1538 (78.0) | 403 (73.9) | 460 (77.6) |  |
 Urban residence basic medical insurance | 874 (14.6) | 422 (14.7) | 256 (13.0) | 100 (18.3) | 96 (16.2) |  |
 Self-pay | 571 (9.6) | 317 (11.0) | 178 (9.0) | 42 (7.7) | 37 (6.2) |  |
COST median (IQR) | 15,151.7 (10,649.7–22,584.9) | 14,160.4 (10,020.2–21,148.3) | 15,243.5 (11,074.0–22,610.8) | 17,936.7 (11,980.8–25,980.4) | 19,339.3 (13,020.7–27,485.9) | < 0.001 |
In-hospital mortality, N (%) | 249 (4.2) | 65 (2.3) | 73 (3.7) | 51 (9.4) | 60 (10.1) | < 0.001 |
Admission year, N (%) | < 0.001 | |||||
 2010 | 397 (6.6) | 217 (7.5) | 144 (7.3) | 23 (4.2) | 13 (2.2) |  |
 2011 | 517 (8.6) | 261 (9.1) | 206 (10.4) | 34 (6.2) | 16 (2.7) |  |
 2012 | 676 (11.3) | 356 (12.4) | 238 (12.1) | 47 (8.6) | 35 (5.9) |  |
 2013 | 635 (10.6) | 336 (11.7) | 211 (10.7) | 53 (9.7) | 37 (6.2) |  |
 2014 | 470 (7.8) | 217 (7.5) | 170 (8.6) | 48 (8.8) | 35 (5.9) |  |
 2015 | 512 (8.6) | 241 (8.4) | 156 (7.9) | 45 (8.3) | 70 (11.8) |  |
 2016 | 557 (9.3) | 257 (8.9) | 157 (8.0) | 50 (9.2) | 93 (15.7) |  |
 2017 | 522 (8.7) | 244 (8.5) | 152 (7.7) | 46 (8.4) | 80 (13.5) |  |
 2018 | 584 (9.8) | 266 (9.2) | 189 (9.6) | 68 (12.5) | 61 (10.3) |  |
 2019 | 617 (10.3) | 283 (9.8) | 192 (9.7) | 70 (12.8) | 72 (12.1) |  |
 2020 | 499 (8.3) | 200 (6.9) | 157 (8.0) | 61 (11.2) | 81 (13.7) |  |