Table 2 Summary of cost effectiveness results based on a 2-year period
| Â | Usual care plus SilAtro-5-90 | Usual care only |
|---|---|---|
Adults and adolescents over 12 years | ||
 Adjuvant therapy | 155.57 | – |
 Antibiotics | 1.67 | 6.16 |
 GP consultations | 58.91 | 84.57 |
 GP—travel time | 78.20 | 112.27 |
 Tonsillectomy surgery | 0.00 | 0.00 |
 Tonsillectomy surgery—travel time | 0.00 | 0.00 |
 Productivity loss | 3.13 | 22.65 |
Total cost (95% CI) | €297.47 (€220.67, €1403.94) | €225.64 (€72.83, €1905.03) |
ATIs (95% CI) | 0.46 (0.00, 2.22) | 0.92 (0.00, 2.98) |
ICER (€/ATI averted) | €156.64 | |
Children aged 6–12 years | ||
 Adjuvant therapy | 77.84 | – |
 Antibiotics | 1.67 | 6.16 |
 GP consultations | 58.91 | 84.57 |
 GP—travel time | 78.20 | 112.27 |
 Tonsillectomy surgery | 0.00 | 0.00 |
 Tonsillectomy surgery—travel time | 0.00 | 0.00 |
 Informal care costs | 3.13 | 22.65 |
Total cost (95% CI) | €219.75 (€142.99, €1,519.65) | €225.64 (€73.16, €2143.82) |
ATIs (95% CI) | 0.46 (0.00, 2.22) | 0.92 (0.00, 2.95) |
ICER (€/ATI averted) | Dominant (intervention has lower costs and better outcomes) | |