Table 1 Characteristics of studies included in the review
From: Patients’ preferences for antiretroviral therapy service provision: a systematic review
Author | Aim of study | Publication year | Country | Type of study | Sample | Sampling method | Method of data collection | Method of data analysis |
|---|---|---|---|---|---|---|---|---|
Zanolini [40] | To quantify preferences for a number of potential clinic improvements to enhance retention | 2018 | Zambia | Quantitative | 385 adult HIV patients who were lost to follow-up | Random | Tablet-based interview | Mixed logit |
Opuni [36] | To measure preferences for characteristics of hypothetical ART clinics | 2010 | South Africa | Quantitative | 510 adult HIV-infected patients | Not stated clearly | Interview | Random intercept logit model |
Tanle [39] | To examine the preferences of PLHIVs concerning ART services | 2017 | Ghana | Qualitative | 145 FGDs and 171 IDIs PLWHIV | Volunteer | FGD and IDI | Thematic analysis |
Rabkin [37] | To explore treatment preferences of PLHIV | 2020 | Zimbabwe | Mixed methods | 35 KIIs, 8 FGDs, and 500 survey participants | Purposive sampling of KIIs and convenience sample of FGD and survey participants | KII and FGD, and tablet-based interview | Framework analysis and Fixed effects logit model |
Strauss [38] | To assess patient preferences for differentiated HIV treatment delivery model characteristics | 2020 | Zimbabwe | Quantitative | 500 stable adults on ART | Purposive | Tablet-based interview | Mixed-effects logit |
Muiruri [35] | To understand preferences for ART packaging | 2020 | Tanzania | Qualitative | 16 adult PLWHIV receiving HIV care | Purposive | In-depth interview | Thematic analysis |
Eshun [34] | To determine what DSD features stable patients on ART most prefer | 2019 | Zambia | Quantitative | 486 adult HIV patients on ART | Random | Tablet-based interview | Mixed logit |
Mühlbacher [54] | To explore patient preferences regarding treatment of HIV/ AIDS | 2013 | Germany | Quantitative | 218 HIV patients | Not stated | Self-administered online or offline | Random effect logit model |
Lloyd [52] | To elicit patient and physician preferences for HIV treatment options | 2013 | United Kingdom | Quantitative | 200 HIV patients | Not stated | Online self-administered | Conditional logit model |
Fuster [51] | To determine HIV patients’ ratings of the characteristics of combined antiretroviral treatment | 2015 | Spain | Quantitative | 602 HIV patients attending external consultations in HIV clinics | Casual or incidental non-probabilistic sampling | Self-administered questionnaire | Exploratory factor analysis, cluster analysis, and Student’s t-test for independent samples |
Brégigeon [50] | To elicit patient preferences regarding the principal characteristics of ARV therapies and to explore satisfaction of PLWH with their current ARV therapies | 2017 | France | Mixed methods | Adult patients taking ART:101 PLWH took part in the quantitative and 31 in the qualitative part | Consecutive | Quantitative interview and IDI | Mixed logit and thematic analysis |
Moyle[53] | To assess the needs of persons living with HIV regarding ART and to investigate the obstacles currently experienced by European patients when taking or commencing therapy | 2003 | France, Germany, Italy, Spain, and the UK | Quantitative | 504 people with HIV | Posters at HIV specialist care centers and through advertisements in patient-oriented magazines, newspapers, and charities | Interview | Descriptive |
Beusterien [41] | To quantify the relative importance of new generation, third-agent HIV drug attributes based on their severity and levels of risk | 2005 | USA | Quantitative | 42 adult HIV-positive individuals | Newspaper advertisement | Computer-administered | Ordinary least squares regression |
Miller [45] | To assess patients preferences for different aspects of antiretroviral regimens | 2002 | USA | Mixed methods | 47 FGD among adult HIV patients on ART and 62 patients for quantitative interview | Consecutive | FGD and quantitative interview | Graded pair-preferences method for the quantitative part but not stated for the qualitative part |
Eaton [42] | To understand patient preferences for contemporary antiretroviral therapy | 2017 | USA | Qualitative | 28 PLWH > = 19 years old who initiated ART on January 1, 2006 | Using flyers, staff referrals, and electronic screens | Nominal group technique | Multi-voting technique |
Yelverton [49] | To identify ART characteristics that are important to patients and understand considerations in ART selection from both patient and provider perspectives | 2018 | USA | Mixed methods | Adult HIV infected individuals on ART: 16 IDIs and 26 for ranking tasks | Patients were recruited by their attending physician, word of mouth, and clinic advertisements | In-depth interviews (IDIs) with HIV patients for the qualitative part and Ranking tasks | Content analysis(qualitative) and count analysis(quantitative) |
Sherer [47] | To evaluate the importance of ART attributes | 2005 | USA | Quantitative | 387 adult HIV-positive patients who were currently receiving or had previously received ART | Convenience sampling using flyers | Interview | Paired sample t-tests |
Ostermann [46] | To quantify patients’ preferences for key characteristics of modern ART | 2020 | USA | Quantitative | 263 adult PLWH | Flyers and invitation cards; referrals from providers, patients, and members of a community advisory board; and recruitment of patients after clinic appointments | Interview | Mixed logit |
Sijstermans [48] | To assess patients’ preferences for HIV treatment in an urban Colombian population | 2020 | Colombia | Quantitative | 224 HIV patients | All patients with HIV in a single City | Self-administered questionnaire | Mixed multinomial logit |
Goossens [23] | To elicit patients’ preferences for HIV treatment in the rural population of Colombia | 2020 | Colombia | Quantitative | 148 HIV patients | All patients with HIV in a single City | Self-administered | Mixed logit model |
Hendriks [44] | To elicit patients’ preferences for HIV/AIDS treatment characteristics in Colombia | 2018 | Colombia | Quantitative | 283 People living with HIV/AIDS | Not clearly stated | Self-administered questionnaire | Hierarchical Bayes method |
Hauber [43] | To estimate the willingness of HIV-positive African American subjects who have chosen not to start ART to accept risks of acute AEs with known outcomes and long-term AEs with uncertain outcomes in exchange for virologic suppression | 2009 | USA | Quantitative | 158 adult HIV-positive but ART-naive individuals | Convenience sampling | Not clearly stated | Mixed-logit |
Beusterien [55] | To assess patient preferences for attributes associated with third agent HIV medications | 2007 | USA and Germany | Quantitative | 323 HIV-positive individuals | Advertisements in an electronic newsletter and newspapers and through HIV clinics | Computerized | Ordinary least squares regression |