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Table 1 Model input parameters with uncertainty ranges in brackets

From: Cost-effectiveness of a reactive oral cholera immunization campaign using Shanchol™ in Malawi

  Central Uncertainty Source of data Assumptions
Parameters value range Central value Uncertainty ranges (min – max)
Economic data  
 Vaccine purchase price per fully immunized, 2016 US$ 3.7 Derived from the analysis
 Vaccine delivery cost per fully immunized, 2016 US$ 3.6 [1.1–3.6] Ilboudo et al. 2017 [14] (Mogasale et al. 2016 [27]—Ilboudo et al. 2017 [14]
 Cost of cholera to patients and households, 2016 US$ 65.6 [43.0–134.0] Ilboudo et al. 2017 [15] (Schaetti et al. 2012 [29]—Poulos et al. 2012 [28]
 Cost of cholera to health facilities, 2016 US$ 59.7 [30.0–61.0] Ilboudo et al. 2017 [15] (Poulos et al. 2012 [28]—Schaetti et al. 2012 [29]
 GDP per capita, 2016 US$ 372.0 World Bank 2017 [31]
 Discount rate (%) 3.0 [1.0–5.0] WHO 2008 [30] (Min and max from WHO, 2008 [30])
Epidemiological data  
 Cholera incidence (Inc, cases per 1,000) 4.0 [3.0–5.0] Sauvageot et al. 2017 [32] (Min and max from Sauvageot et al. 2017 [32])
 Case fatality rate (CFR, %) 2.6 [1.4–6.7] M’Bangombé, 2017 [33] (Min and max from M’Bangombé, 2017 [33])
 Vaccine protective duration (Dur, years) 5.0 [3.0–5.0] Bhattacharya et al. 2013 [9] (Min and max from Bhattacharya et al. 2013 [9])
 Length of illness (Length, days) 5.0 [4.0–7.0] Ilboudo et al. 2017 [15] (Poulos et al. 2012 [28]—Schaetti et al. 2012 [29])
 DALY weight (DALY weight) 0.2 [0.1–0.3] Salomon et al. 2012 [36] (Min and max from Salomon et al. 2012 [36])
 Vaccine Efficacy (VEff, no indirect protection) 58.0 [42.0–69.0] Bi et al. 2017 [35] (Min and max from Bi et al. 2017 [35])
 Vaccine Efficacy (VEff, with indirect protection) 93.0 [82.0–99.0] Longini et al. 2007 [24] (Min and max from Longini et al. 2007 [24])
 Campaign coverage rate (%, without indirect protection) 58.0 [53.0–91.0] MSF 2016 [4] (Min and max from MSF, 2016 [34])
Demographic  
 Population 90 000.0
 Life expectancy at infection (LExp, years) 58.0 [50.0–60.0] WHO, 2016 [37] (Min and Max from WHO, 2016 [37])
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