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Table 1 General information on selected BIAs

From: A systematic review of the budget impact analyses for antitumor drugs of lung cancer

First author

Year

Country

Drugs

Research foundation

Population size, characteristics

Carlson [31]

2011

US

Erlotinib

Model

500,000 member US health plan; stage IIIB/IV NSCLC.

Farsai [39]

2011

Thailand

Pemetrexed

Model

Lung cancer patients in the hospital

Sumitra [40]

2012

Thailand

Gefitinib

Model

100,000 advanced NSCLC patients

Preeti [32]

2014

US

Erlotinib

Model

500,000 member health plan; with advanced NSCLC

Lisa [33]

2016

US

Ramucirumab + docetaxel

Model

150,000 patients in hospital; NSCLC Patients Receiving 2nd line Therapy

Mengyuan [41]

2016

China

Gefitinib

Model

74000 advanced NSCLC patients

Sumitra [42]

2017

Thailand

Crizotinib

Model

5183 NSCLC in lung cancer patient; aged ≧19 years

Daniel [34]

2017

US

Pembrolizumab

Model

19601 NSCLC patients with PD-L1 expression ≧ 50%

Jan [43]

2017

Norway

Pembrolizumab

Model

3035 cases; Patients with advanced NSCLC 2nd line treatment

Pedro [44]

2018

South American countries

Pembrolizumab

RCT

3043 participants; patients with NSCLC for immunotherapy

Christopher [35]

2018

US

Necitumumab

Model

100,000 plan participants; msqNSCLC patients receiving first-line chemotherapy; aged≧65 years

Jonathan [36]

2018

US

Afatinib

Model

Health plan for 1,000,000 people; metastatic NSCLC whose tumors have EGFR del19 or L858R mutations initiating first-line treatment; age ≥ 18 years

Xueyan [45]

2018

China

Icotinib

Model

73,400 patients with advanced NSCLC who were genetically tested and eligible for icotinib in the insured population

Jie [46]

2019

China

Afatinib

Model

45,554 patients with advanced NSCLC who were positive for EGFR mutation after chemotherapy in the insured population

  1. RCT Randomized controlled trial, NSCLC non-small cell lung cancer, msqNSCLC metastatic squamous non-small cell lung cancer