Table 3 Budget impact analysis of Contingent NIPT(SIPS + NIPT) compared to current screening practice (SIPS): baseline results
Items | Number of procedures | Costs (CAD$) | Costs difference (Contingent NIPT minus Current practice) | ||
|---|---|---|---|---|---|
Current practice (SIPS) | Contingent NIPT (SIPS + NIPT) | Current practice (SIPS) | Contingent NIPT (SIPS + NIPT) | ||
Screening tests | |||||
 SIPS | 41,904 | 41,904 | 4,550,887 | 4,550,887 | $ 0 |
 NIPT | 0.00 | 1809 | 0 | 1,437,863 | $ +1,437,863 |
Total for screening tests | 4,550,887 | 5,988,750 | $ +1,437,863 | ||
Invasive tests (Amniocentesis and karyotype) | 1773 | 103 | 1,532,710 | 89,420 | $ −1,443,290 |
 Other procedures | |||||
  Genetic counselling | 114 | 101 | 15,777 | 14,049 | $ −1728 |
  Procedure related loss | 2 | 0.1 | 5693 | 332 | $ −5361 |
  Hospitalization for amniotic fluid leakage | 18 | 1 | 52,681 | 3073 | $ −49,607 |
  Termination of pregnancy (Confirmed DS) | 102 | 91 | 167,199 | 148,890 | $ −18,309 |
  Program administration | 41,904 | 41,904 | 757,339 | 757,339 | $ 0 |
Total for other procedures | 998,688 | 923,683 | $ −75,005 | ||
Overall | 7,082,285 | 7,001,853 | $ −80,432 95% CI ($ −81,462 to $ −79,874) | ||