Introducing cell-free DNA noninvasive testing in a Down syndrome public health screening program: a budget impact analysis

Table 2 Unit costs (CAD$)

Items	Baseline unit cost (CAD$)	Values for sensitivity analyses	Source
Current screening practice	108.60		[14, 42, 46]
NIPT (including interpretation)	795	100–1000	[19, 48]
Amniocentesis (including karyotype and its interpretation)	864.39	600–1000	[14, 42, 47]
Genetic counselling	138.636		[14]
Program administration	18.07		[14, 45, 49]
Termination of pregnancy in case of confirmed DS	1,632,48
Amniocentesis related loss	291,900
Hospitalization after amniotic fluid leakage related to amniocentesis	297,100

ISSN: 1478-7547