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Table 2 Base case results

From: Cost-effectiveness analysis of ceritinib vs. crizotinib in previously untreated anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) in Hong Kong

 

Ceritinib (450 mg)

Crizotinib

Ceritinib vs. Crizotinib

Cost (USD)

 Drug and drug administration costs, initial treatment

82,215

82,623

− 408

 Drug and drug administration costs, post-progression treatment

10,392

9,921

471

 Treatment associated adverse event costs

1,982

1,197

785

 Medical costs

62,992

56,683

6,309

 Total costs

157,581

150,424

7,157

Effectiveness

 Total QALYs

3.22

2.68

0.54

 Total LYs

4.51

3.85

0.66

Incremental cost-effectiveness ratio (ICER) (USD)

 Incremental cost per QALY gained

  

13,343

 Incremental cost per LY gained

  

10,794

  1. ICER, incremental cost-effectiveness ratio; LY, Life-year; mg, milligram; QALY, quality-adjusted life year; USD, United States Dollar