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Table 3 Treatment and administration cost inputs

From: Cost effectiveness of nusinersen for patients with infantile-onset spinal muscular atrophy in US

Strategy

Administration

Package size

WAC* per package

Estimated net cost per package

Source

Nusinersen treatment cost

Intrathecal injection

2.4 mg/ml (5 ml)

$125,000

$127,500

Magellan 2016 [20]; Redbook 2018 [21]

Administration cost

$1209

Assuming 40% of patients receive nusinersen in inpatient settings

Physician fee schedule 2018; [22] Nationwide Children’s Hospital [23]

  1. *Wholesale acquisition cost (WAC) as of July 1, 2019
  2. AWP–15%, where AWP is $150,000 per package as of July 1, 2019