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Table 3 Vaccination cost estimates and intervention costs in 2018 US$

From: Introduction of birth dose of hepatitis B virus vaccine to the immunization program in Ethiopia: an economic evaluation

Parameter

Base assumptions

Range for sensitivity analysis

Source

Vaccination cost

Recurrent costs

   Vaccinea

0.25200

–

[23, 29]

   Syringes and safety boxb

0.04824

–

[23, 30]

   Transport and maintenance

0.02206

–

[12, 31]

   Cold chain storage

0.02213

–

[12, 31]

  Capital costs

   Social mobilization

0.05276

–

[12, 31]

   Training

0.34532

–

[12, 31]

  Total average costs per vaccinated child

0.74251

0.50–1.00

 

Medical care costs (US$)

  Initial assessment and diagnosis cost

113.16

56.58–226.32

Local data

  Drug treatment

60.35

30.17–120.70

[32, 33]

  Monitoring on treatment

37.00

18.50–74.00

Local data

  Monitoring without treatment

18.50

9.25–37.00

Local data

  Average annual cost of hospital admission for decompensated cirrhosis

153.88

76.94–307.76

[34]

  Average annual cost of hospital admission for hepatocellular carcinoma

153.88

76.94–307.76

[34]

  Treatment cost of symptomatic acute infection

40.00

20.00–80.00

Assumptions

  Treatment cost of fulminant hepatitis

200.00

100.00–400.00

Assumptions

  1. aVaccine wastage rate was assumed to be 20% and a freight rate of 6%
  2. bWastage and freight rates were 10% and 15%, respectively