Table 1 Data abstracted from MESCC RCT PFS and OS analyses
From: A technique for approximating transition rates from published survival analyses
| Â | Description | RT-alone arm | mS+RT arm |
|---|---|---|---|
PFS analysis | |||
\(N_{pfs}^e\) | Total number of PFS events | 17 | 31 |
\(N_{pfs}^c\) | Total number of patients censored from PFS analysis | 5 | 6 |
\(\sum \limits _{i=1}^{N_{pfs}^e}p_i^e\) | Person-time of PFS observation | 7.02 years | 27.22 years |
\(\tau _{pfs}\) | Maximum observation time in the PFS analysis | 2.97 years | 5.25 years |
\(AUC_{pfs}\) | Area under PFS curve | 0.63 | 1.16 |
OS analysis | |||
\(N_{os}^e\) | Total number of OS events | 44 | 45 |
\(N_{os}^c\) | Total number of patients censored from OS analysis | 1 | 3 |
\(\tau _{os}\) | Maximum observation time in the OS analysis | 2.99 years | 5.25 years |
\(\sum \limits _{i=1}^{N_{os}^e}o_i^e\) | Person-time of OS observation | 24.17 years | 35.89 years |
\(AUC_{os}\) | Area under OS curve | 0.62 | 0.98 |
Synthesis of PFS and OS analyses | |||
\(N_{simul}\) | Total number of simultaneous events in PFS and OS curves | 10 | 19 |