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Table 2 Sensitivity and specificity on the basis of the screening cut-off.

From: The consequences of implementing non-invasive prenatal testing with cell-free foetal DNA for the detection of Down syndrome in the Spanish National Health Service: a cost-effectiveness analysis

Risk cut-off point

TP

FP

FN

TN

Sensitivity (%)

Specificity (%)

FPR (%)

FNR (%)

1:270

219

2.45

25

53.88

89.75

95.65

4.35

10.25

1:500

225

3.99

19

52.34

92.21

92.91

7.09

7.79

1:1000

230

7.19

14

49.14

94.26

87.23

12.77

5.74

  1. FN, false negative; FNR, false-negative ratio; FP, false positive; FPR, false positive ratio; TN, true negative; TP, true positive
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