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Table 2 Sensitivity and specificity on the basis of the screening cut-off.

From: The consequences of implementing non-invasive prenatal testing with cell-free foetal DNA for the detection of Down syndrome in the Spanish National Health Service: a cost-effectiveness analysis

Risk cut-off point TP FP FN TN Sensitivity (%) Specificity (%) FPR (%) FNR (%)
1:270 219 2.45 25 53.88 89.75 95.65 4.35 10.25
1:500 225 3.99 19 52.34 92.21 92.91 7.09 7.79
1:1000 230 7.19 14 49.14 94.26 87.23 12.77 5.74
  1. FN, false negative; FNR, false-negative ratio; FP, false positive; FPR, false positive ratio; TN, true negative; TP, true positive