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Table 6 Cost-effectiveness analyses for base case and sensitivity analyses per QALY

From: Comparative cost-effectiveness of surgery, angioplasty, or medical therapy in patients with multivessel coronary artery disease: MASS II trial

 

Cost, $

QALYs

ICER ($/QALYs)

% Dominant

% Dominated

≤ 3 GDP/capita

≤ $100,000

PCI

MT

Δ (PCI–MT)

Δ (95% CI)

PCI

MT

Δ (PCI–MT)

Δ (95% CI)

Overall (n = 391)

3002

1740

1262

(994; 1513)

3.80

3.54

0.26

(0.07; 0.45)

4854

0

0

99

99

Overall and additional cost (n = 391)

3131

1764

1366

(1095; 1630)

3.80

3.54

0.26

(0.07; 0.45)

5255

0

1

98

99

Higher cost (n = 391)

78,063

45,253

32,811

(25,837; 39,331)

3.80

3.54

0.26

(0.07; 0.45)

126,197

0

6

0

25

 

Cost, $

QALYs

ICER ($/QALYs)

% Dominant

% Dominated

≤ 3 GDP/capita

≤ $100,000

CABG

MT

Δ (CABG–MT)

Δ (95% CI)

CABG

MT

Δ (CABG–MT)

Δ (95% CI)

Overall (n = 385)

2753

1740

1013

(761; 1235)

3.77

3.54

0.23

(0.03; 0.42)

4403

0

1

97

98

Overall and additional cost (n = 385)

2772

1764

1008

(757; 1234)

3.77

3.54

0.23

(0.03; 0.42)

4384

0

1

97

98

Higher cost (n = 385)

71,583

4525

26,331

(19,782; 32,111)

3.77

3.54

0.23

(0.03; 0.42)

114,482

0

8

0

36

 

Cost, $

QALYs

ICER ($/QALYs)

% Dominant

% Dominated

≤ 3 GDP/capita

≤ $100,00

PCI

CABG

Δ (PCI–CABG)

Δ (95% CI)

PCI

CABG

Δ (PCI–CABG)

Δ (95% CI)

Overall (n = 382)

3002

2753

249

(64; 445)

3.80

3.77

0.03

(− 0.14; 0.21)

8308

0

35

61

64

Overall and additional cost (n = 382)

3130

2772

358

(160; 565)

3.80

3.77

0.03

(− 0.14; 0.21)

11,938

0

35

60

64

Higher cost (n = 382)

78,064

71,583

6480

(1672; 11,566)

3.80

3.77

0.03

(− 0.14; 0.21)

216,014

0

43

4

38

  1. 5000 replications
  2. MT medical treatment, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, CI confidence interval, QALY quality-adjusted life-year, $ American dollar, GDP gross domestic product, Δ difference