Unit cost (US$) | Recommended dosage/frequency | Cost per month (30 days) | |
---|---|---|---|
Drug therapy costs | |||
Sorafenib | 1888 (60a 200 mg) | 400 mg twice per day | 3777 |
FOLFOX4 | ≈ 2.14 treatment cycles per month | 1865 | |
Oxaliplatin | 290 (50 mg) | 138 mg per cycle | 1716 |
5 FU | 8 (400 mg) | 3247 mg per cycle | 132 |
LV | 16 (1225 mg) | 649 mg per cycle | 18 |
Unit cost (US$) | Incidence | ||
---|---|---|---|
Sorafenib | FOLFOX4 | ||
Other medical costs | |||
General warda | 8/day | / | 5 days per cycle |
Testsb | 155/set | Once per month | Once per cycle |
Adverse event | Cost/event | ||
Nausea + vomiting | 65 | 11.4% | 41.0% |
Abnormal | |||
AST/ALT values | 59 | 0.0% | 31.7% |
Alopecia | 0 | 24.8% | 0.0% |
Anorexia | 26 | 12.8% | 26.8% |
Bilirubin | 349 | 0.0% | 20.2% |
Fatigue | 3 | 20.1% | 17.5% |
Diarrhea | 13 | 25.5% | 15.9% |
Sensory neuropathy | 3 | 0.0% | 15.3% |
HFSR | 4 | 45.0% | 0.0% |
Rash | 7 | 20.1% | 0.0% |
Hypertension | 37 | 18.8% | 0.0% |
Bone marrow suppression | 79 | 0.0% | 68.9% |