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Table 5 Probabilistic analysis (5000 iterations): proportions (%) of pairs of incremental cost and incremental severe adverse neonatal events associated with CL < 15 mm or CL [16–30 mm] and fFN qualitative compared to each of the six other strategies

From: Cost-effectiveness of diagnostic tests for threatened preterm labor in singleton pregnancy in France

 

∆E < 0 and ∆C < 0a

∆E < 0 and ∆C > 0b

∆E > 0 and ∆C < 0c

∆E > 0 and ∆C > 0d

Strategies [24–27] GA

 S6: CL < 15 mm

90

1

0

9

 Sref: CL < 25 mm

24

47

0

29

 S2: Qualitative fFN

20

47

0

33

 S3: Quantitative fFN

26

23

0

51

 S4: Cervical IL-6

41

18

0

41

 S5: CL < 18 mm, plasma RANTES and plasma IL-10

27

24

0

49

Strategies [28–31] GA

 S6: CL < 15 mm

92

0

3

5

 Sref: CL < 25 mm

28

45

0

27

 S2: Qualitative fFN

24

45

0

31

 S3: Quantitative fFN

28

20

0

52

 S4: Cervical IL-6

44

17

0

39

 S5: CL < 18 mm, plasma RANTES and plasma IL-10

28

23

0

49

Strategies [32–34] GA

 S6: CL < 15 mm

96

0

3

1

 Sref: CL < 25 mm

59

25

3

13

 S2: Qualitative fFN

54

26

3

17

 S3: Quantitative fFN

43

12

5

41

 S4: Cervical IL-6

55

10

3

31

 S5: CL < 18 mm, plasma RANTES and plasma IL-10

45

14

5

36

  1. GA gestational age, CL cervical length, fFN fetal fibronectin, IL interleukin
  2. a The southwest quadrant (SW) represented the proportion where CL < 15 mm or CL [16–30 mm] and fFN qualitative dominated the alternative strategies
  3. b The northwest quadrant (NW) represented the proportion where CL < 15 mm or CL [16–30 mm] and fFN qualitative was more effective but more costly
  4. c The southeast quadrant (SE) represented the proportion where CL < 15 mm or CL [16–30 mm] and fFN qualitative was less effective and less costly
  5. d The northeast quadrant (NE) represented the proportion where CL < 15 mm or CL [16–30 mm] and fFN qualitative was less effective and more costly