Table 4 Deterministic sensitivity analyses
From: Cost-effectiveness of diagnostic tests for threatened preterm labor in singleton pregnancy in France
|  | Cost per mother–child, € | Neonatal serious adverse events | ICERa, € |
|---|---|---|---|
Minimum values of sensitivity and maximum values of specificity | |||
S7: CL < 15 mm or CL [16–30 mm] and qualitative fFN | 3040 | 0.0219 | – |
S2: Qualitative fFN | 4359 | 0.0258 | 338,205 |
S5: CL < 18 mm, plasma RANTES and plasma IL-10 | 4382 | 0.0260 | 327,317 |
Sref: CL < 25 mm | 4388 | 0.0261 | 320,952 |
S4: Cervical IL6 | 4465 | 0.0269 | 285,000 |
S3: Quantitative fFN | 4492 | 0.0269 | 290,400 |
S6: CL < 15 mm | 4592 | 0.0264 | 344,889 |
Maximum values of sensitivity and minimum values of specificity | |||
S7: CL < 15 mm or CL [16–30 mm] and qualitative fFN | 3300 | 0.0236 | – |
S2: Qualitative fFN | 4381 | 0.0260 | 450,417 |
S5: CL < 18 mm, plasma RANTES and plasma IL-10 | 4414 | 0.0264 | 397,857 |
Sref: CL < 25 mm | 4427 | 0.0265 | 388,621 |
S4: Cervical IL-6 | 4465 | 0.0269 | 353,030 |
S3: Quantitative fFN | 4473 | 0.0270 | 345,000 |
S6: CL < 15 mm | 4653 | 0.0268 | 422,813 |
Incidence of preterm birth of 5% | |||
S7: CL < 15 mm or CL [16–30 mm] and qualitative fFN | 1927 | 0.0119 | – |
S3: Quantitative fFN | 3517 | 0.0168 | 324,490 |
Sref: CL < 25 mm | 3560 | 0.0172 | 308,113 |
S4: Cervical IL-6 | 3560 | 0.0172 | 308,113 |
S2: Qualitative fFN | 3587 | 0.0175 | 296,429 |
S5: CL < 18 mm, plasma RANTES and plasma IL-10 | 3604 | 0.0177 | 289,138 |
S6: CL < 15 mm | 3719 | 0.0143 | 746,667 |
Incidence of preterm birth of 15% | |||
S7: CL < 15 mm or CL [16–30 mm] and qualitative fFN | 4121 | 0.0337 | – |
Sref: CL < 25 mm | 5414 | 0.037 | 391,818 |
S3: Quantitative fFN | 5437 | 0.0373 | 365,556 |
S5: CL < 18 mm, plasma RANTES and plasma IL-10 | 5443 | 0.0374 | 357,297 |
S2: Qualitative fFN | 5452 | 0.0374 | 359,730 |
S4: Cervical IL-6 | 5514 | 0.0381 | 316,591 |
S6: CL < 15 mm | 5636 | 0.0295 | − 360,714 |