Table 2 Model results: lifetime horizon
| Â | Analysis 1 (UMEC vs TIO) | Analysis 2 (UMEC vs GLY) | ||
|---|---|---|---|---|
TIO | UMEC | GLY | UMEC | |
Cumulative number of exacerbations | ||||
 Moderate | 4.926 | 4.924 | 4.952 | 4.951 |
 Severe | 1.659 | 1.608 | 1.636 | 1.604 |
 TOTAL | 6.585 | 6.532 | 6.588 | 6.555 |
 Severe exacerbations PPPY | 0.186 | 0.177 | 0.184 | 0.178 |
 Total exacerbations PPPY | 0.740 | 0.718 | 0.740 | 0.726 |
Outcomes | ||||
 Accumulated LYs (undiscounted) | 8.902 | 9.097 | 8.906 | 9.029 |
 Accumulated QALYs | 5.003 | 5.121 | 5.038 | 5.139 |
Costs | ||||
 Accumulated costs (total) | £12,800 | £12,300 | £11,800 | £12,000 |
 Drug costs | £3180 | £2560 | £2510 | £2540 |
 Non-drug costs | £9590 | £9760 | £9310 | £9420 |
 Hospital costs | £8800 | £8960 | £8550 | £8640 |
 Outpatient/hospital/clinic costs | £504 | £514 | £480 | £486 |
 Physician visits (office, home, day or night) | £288 | £292 | £288 | £290 |
Incremental results (95% CI), UMEC vs comparator | ||||
 Incremental exacerbations |  | − 0.053 (− 0.171, 0.028) |  | − 0.033 (− 0.135, 0.017) |
 Incremental cost |  | − £460 (− £645, − £240) |  | £132 (£12, £330) |
 Incremental LYs |  | 0.195 (0.069, 0.356) |  | 0.124 (0.015, 0.281) |
 Incremental QALYs |  | 0.118 (0.055, 0.191) |  | 0.101 (0.043, 0.179) |
 ICER (QALY) |  | Dominant |  | £1310 (£284, £2060) |
 ICER (LY) |  | Dominant |  | £1070 (£718, £1520) |