Parameters/utility measures | Valuables | Distribution | Source |
---|---|---|---|
(a) Probabilistic parameters and utility measures | |||
Annual incidence of Dysmenorrhea | 0.0008–0.007 | Age-dependent | National Patient Survey (2011) [9] |
Progress from dysmenorrhea to endometriosis I/II | 18.4% | Beta | Taketani et al. (1997) [1] |
Natural healing in dysmenorrhea | 80% | – | Assumption:adjusted by calibration |
Natural healing in endometriosis I/II | 40% | – | Assumption:adjusted by calibration |
Natural healing in endometriosis III/IV | 80% | – | Assumption:adjusted by calibration |
Recurrence | 22.2% | Beta | Taketani et al. (1997) [1] |
Visit proportion for dysmenorrhea | 0.03–0.5 | Age-dependent | Calculation from Taketani et al. (1997) [1] and National Patient Survey (2011) [9] |
Visit proportion for endometriosis | 0.0124–0.0307 | Age-dependent | |
Surgery for endometriosis | 6.0% | Normal | Tanaka et al. (2013) [6] |
Proportion of OTC use for self-medication | 87.1% | Normal | Tsutsumi et al. (2002) [28] |
Annual other-cause death | Age-dependent | – | Life-time table (2013) [10] |
Odds ratio for risk reduction in the development of endometriosis I/II | 0.40 | LogNor | Vessey et al. (1993) [11] |
Odds ratio for risk reduction in the progression to endometriosis III/IV | 0.10 | LogNor | |
Utility for dysmenorrhea | 0.637 | LogNor | Assumed that utility for dysmenorrhea is the same as that for endometriosis I/II |
Utility for endometriosis I/II | 0.637 | LogNor | Institution-based QOL survey using visual analogue scales |
Utility for endometriosis III/IV | 0.549 | LogNor | |
Utility for cured | 1.000 | – | Assumption |
Costs (JPY)/utilizations | Valuables | Distribution | Source |
---|---|---|---|
(b) Cost parameters and resource utilizations | |||
Annual frequency of visits for dysmenorrhea | 4 | – | Assumption |
Visit cost for dysmenorrhea | 7529 | LogNor | Resource utilization survey (2011) [16] |
Annual frequency of visits for endometriosis | 4 | – | Assumption |
Visit cost for endometriosis | 11,291 | LogNor | Resource utilization survey (2011) [16] |
Annual inpatient cost (excl. surgery cost) | 207,661 | LogNor | |
Cost of surgery (mild) | 288,080 | LogNor | National insurance price list established by the surgeons’ group (2014) [29] |
Cost of surgery (complex) | 456,667 | LogNor | |
Proportion of complex casesa | 45.2% | LogNor | Nagata et al. (1982) [30] |
Annual OTC cost used (self-care) | 19,243 | LogNor | Recalculation of raw data from Tanaka et al. (2013) [6] |
Annual self-medication cost (self-care) | 13,715 | LogNor | |
Productivity loss (half year, self-care) | 184,625 | LogNor | |
Productivity loss (half year, guideline-based intervention) | 39,546 | LogNor |