Incorporating economies of scale in the cost estimation in economic evaluation of PCV and HPV vaccination programmes in the Philippines: a game changer?

Table 5 Incremental cost-effectiveness ratio of PCV vaccination compared to no vaccination

% coverage	PCV10 (USD/QALY)			PCV13 (USD/QALY)
% coverage	Without taking into account EoS approach	With EoS approach	% reduction of ICER	Without taking into account EoS approach	With EoS approach	% reduction of ICER
10^a	2655	1052	62	1997	760	71
20^a	2655	975	65	1997	697	74
30^a	2655	923	67	1997	650	75
40^a	2655	877	70	1997	609	77
50^a	2655	834	72	1997	569	79
60^a	2655	792	73	1997	530	80
70^a	2655	750	75	1997	491	81
80^b	1439	134	97	1162	31	98
90^b	1533	151	97	1232	38	98
100^b	1614	159	97	1292	38	98

Herd protection was considered at a vaccination coverage rate of 80%
PCV pneumococcal conjugate vaccine, EoS economies of scale, ICER incremental cost-effectiveness ratio
^aLow vaccination coverage
^bHigh vaccination coverage

ISSN: 1478-7547